Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:8936
Official Symbol:WASF1
Other Aliases:FLJ31482|KIAA0269|SCAR1|WAVE|WAVE1
See related:HGNC:12732|MIM:605035|HPRD:05434
Chromosome:6
Location:6q21-q22
Gene Description:WAS protein family, member 1
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0291
ORGANISM:human
Entrez Gene ID:8936
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:15816859
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Prefrontal Cortex
Drug Effects:Upregulated
Fold Change:0.67
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
83767CBCerebellum100.0100.0
83767CTXCerebral cortex100.0100.0
83767HIPHippocampal region100.0100.0
83767HPFHippocampal formation100.0100.0
83767HYHypothalamus89.390235900878984.0417404174805
83767LSXLateral septal complex100.0100.0
83767MBMidbrain97.8868103027344100.0
83767MYMedulla94.0304565429688100.0
83767OLFOlfactory bulb100.0100.0
83767PPons83.570899963378995.090087890625
83767PALPallidum77.489295959472782.2973480224609
83767RHPRetrohippocampal region100.0100.0
83767sAMYStriatum-like amygdalar nuclei100.0100.0
83767STRStriatum100.0100.0
83767STRdStriatum dorsal region100.0100.0
83767STRvStriatum ventral region100.0100.0
83767THThalamus100.0100.0
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
8936GO:0003779IEAFunctionactin binding
8936GO:0006461NASProcessprotein complex assembly
8936GO:0006928TASProcesscell motility
8936GO:0015629TASComponentactin cytoskeleton
8936GO:0030041TASProcessactin filament polymerization
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
-9051NP_003969.2proline-serine-threonine phosphatase interacting protein 1HPRD05891
-9901NP_055665.1SLIT-ROBO Rho GTPase activating protein 3 isoform aHPRD12108
-23268NP_056036.1dynamin binding proteinHPRD10918
NP_003922.1--ActinHPRD05434
NP_003922.1---BIND182767
NP_003922.19051-PSTPIP1HPRD05434
NP_003922.19901NP_055665.1SLIT-ROBO Rho GTPase activating protein 3 isoform aBIND12361
NP_003922.155845NP_060932.2chromosome 3 open reading frame 10HPRD12818
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
8936WASF1_HUMANQ92558IPR000480GlutelinGlutelin
8936WASF1_HUMANQ92558IPR003882Pistil_extensinPistil-specific extensin-like protein
8936WASF1_HUMANQ92558IPR000694PRO_richProline-rich region
8936WASF1_HUMANQ92558IPR003267Small_Pro_richSmall proline-rich
8936WASF1_HUMANQ92558IPR003124WH2_actin_bdActin-binding WH2

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