Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:9001
Official Symbol:HAP1
Other Aliases:HAP2|HIP5|HLP|hHLP1
See related:HGNC:4812|MIM:600947|HPRD:02972
Chromosome:17
Location:17q21.2-q21.3
Gene Description:huntingtin-associated protein 1 (neuroan 1)
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0085
ORGANISM:human
Entrez Gene ID:9001
Evidence Type:Mapping from mouse
Evidence ID Type:Entrez Gene
Evidence ID:15114
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
15114CBCerebellum21.54501533508324.6879971027374
15114CTXCerebral cortex54.486220359802251.012951374054
15114HIPHippocampal region73.381331443786683.071346282959
15114HPFHippocampal formation71.374750137329177.3973121643066
15114HYHypothalamus100.0100.0
15114LSXLateral septal complex100.0100.0
15114MBMidbrain95.583480834960998.1644344329834
15114MYMedulla73.289752006530886.0500802993774
15114OLFOlfactory bulb100.099.4914493560791
15114PPons69.33819198608478.1729001998901
15114PALPallidum94.673526763916100.0
15114RHPRetrohippocampal region65.723927497863866.2175626754761
15114sAMYStriatum-like amygdalar nuclei100.0100.0
15114STRStriatum86.752639770507884.7328109741211
15114STRdStriatum dorsal region53.257881164550839.1106946468353
15114STRvStriatum ventral region100.0100.0
15114THThalamus39.730751037597747.3209629058838
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
9001GO:0005554NDFunctionmolecular function unknown
9001GO:0007268TASProcesssynaptic transmission
9001GO:0007275NRProcessdevelopment
9001GO:0015629TASComponentactin cytoskeleton
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
-9146NP_004703.1hepatocyte growth factor-regulated tyrosine kinase substrateHPRD05085
NP_003940.2--Dynactin 1HPRD02972
NP_003940.29146-HrsHPRD02972
NP_003940.229117AAF19526.1Homo sapiens bromodomain protein CELTIX1 mRNA, complete cds.HPRD12531
NP_003940.29001NP_003940.2huntingtin-associated protein 1 isoform 1HPRD02972
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
9001IPR006933HAP1_NHAP1, N-terminal
9001IPR000533TropomyosinTropomyosin
9001HAP1_HUMANP54257IPR006933HAP1_NHAP1, N-terminal

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