Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:9079
Official Symbol:LDB2
Other Aliases:CLIM1|LDB1
See related:HGNC:6533|MIM:603450|HPRD:16022
Chromosome:4
Location:4p16
Gene Description:LIM domain binding 2
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0136
ORGANISM:human
Entrez Gene ID:9079
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:12629581
Addiction Drug:COCAINE
Addiction Drug Detail:COCAINE ABUSE
Addiction Brain Area:Dorsolateral Prefrontal Cortex
Drug Effects:Upregulated/Downregulated
Fold Change:1.23 :: 2.22 :: 2.53 :: 1.98 :: -2.34 :: -1.81 :: -1.32
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
16826CBCerebellum9.7139453887939513.0809602737427
16826CTXCerebral cortex14.382436275482212.3460125923157
16826HIPHippocampal region6.03874194622047.53943085670471
16826HPFHippocampal formation13.608200073242213.8192603588104
16826HYHypothalamus9.35326123237617.81629729270935
16826LSXLateral septal complex9.281960248947148.20574104785919
16826MBMidbrain6.998417854309086.52121639251709
16826MYMedulla10.382733821868910.6888015270233
16826OLFOlfactory bulb11.587413072586111.1247112751007
16826PPons13.053821086883511.6845283508301
16826PALPallidum6.098453879356384.94081690907478
16826RHPRetrohippocampal region24.246904850006120.959734916687
16826sAMYStriatum-like amygdalar nuclei3.686849594116212.96437066793442
16826STRStriatum5.207847833633424.55985915660858
16826STRdStriatum dorsal region2.940890908241272.74582731723785
16826STRvStriatum ventral region10.16194033622747.97118246555328
16826THThalamus5.511628866195684.62044382095337
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
9079GO:0003712IEAFunctiontranscription cofactor activity
9079GO:0003712TASFunctiontranscription cofactor activity
9079GO:0005634IEAComponentnucleus
9079GO:0007275IEAProcessdevelopment
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_001281.151132-Ring finger protein 12HPRD16022
NP_001281.156956NP_064589.2LIM homeobox 9 isoform 1HPRD16022
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
9079LDB2_HUMANO43679IPR002691LIM_bdLIM binding protein

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