Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:9118
Official Symbol:INA
Other Aliases:MGC12702|NEF5|NF-66|TXBP-1
See related:HGNC:6057|MIM:605338|HPRD:05628
Chromosome:10
Location:10q24.33
Gene Description:internexin neuronal intermediate filament protein, alpha
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIP0254
ORGANISM:human
Entrez Gene ID:9118
Evidence Type:Proteomics
Evidence ID Type:PUBMED
Evidence ID:16172612
Addiction Drug:ALCOHOL
Addiction Drug Detail:Chronic alcohol use
Addiction Brain Area:Brain
Drug Effects:Downregulated
Fold Change:-1.2::-1.3;1.4::1.5;1.5::1.6;-1.2;-1.1::-1.6-1.1::-1.6
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
226180CBCerebellum96.6103591918945100.0
226180CTXCerebral cortex100.0100.0
226180HIPHippocampal region100.0100.0
226180HPFHippocampal formation100.0100.0
226180HYHypothalamus100.0100.0
226180LSXLateral septal complex100.0100.0
226180MBMidbrain100.0100.0
226180MYMedulla99.6834335327148100.0
226180OLFOlfactory bulb100.0100.0
226180PPons100.0100.0
226180PALPallidum91.006275177002100.0
226180RHPRetrohippocampal region100.0100.0
226180sAMYStriatum-like amygdalar nuclei100.0100.0
226180STRStriatum100.0100.0
226180STRdStriatum dorsal region100.0100.0
226180STRvStriatum ventral region100.0100.0
226180THThalamus100.0100.0
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
9118GO:0005200TASFunctionstructural constituent of cytoskeleton
9118GO:0005883TASComponentneurofilament
9118GO:0007399IEAProcessnervous system development
9118GO:0030154IEAProcesscell differentiation
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_116116.185461NP_203752.1TPR domain, ankyrin-repeat and coiled-coil-containingHPRD18146
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
9118AINX_HUMANQ16352IPR006821filament_DNA_bdIntermediate filament, DNA-binding region
9118AINX_HUMANQ16352IPR001664IFIntermediate filament protein
9118AINX_HUMANQ16352IPR002957Keratin_IKeratin, type I

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