Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:91612
Official Symbol:CHURC1
Other Aliases:C14orf52|FLJ33064|My015|chch
See related:HGNC:20099|MIM:608577|HPRD:12262
Chromosome:14
Location:14q23.3
Gene Description:churchill domain containing 1
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0080
ORGANISM:human
Entrez Gene ID:91612
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:15009677
Addiction Drug:COCAINE
Addiction Drug Detail:COCAINE ABUSE
Addiction Brain Area:Nucleus Accumbens
Drug Effects:Downregulated
Fold Change:0.46 :: -0.36 :: -0.94 :: 0.93 :: -1.85 :: -0.29 :: -1.03 :: 0.71 :: -1.22 :: 1.04
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
211151CBCerebellum21.781248092651425.3560752868652
211151CTXCerebral cortex86.029350280761762.9902458190918
211151HIPHippocampal region41.877819061279348.0182113647461
211151HPFHippocampal formation52.74810409545954.3066902160645
211151HYHypothalamus31.09209823608423.8839244842529
211151LSXLateral septal complex31.094264984130922.0716552734375
211151MBMidbrain35.281776428222729.9482345581055
211151MYMedulla38.017921447753940.0807075500488
211151OLFOlfactory bulb58.836292266845748.3304862976074
211151PPons42.49419784545940.8408851623535
211151PALPallidum32.848342895507829.1287479400635
211151RHPRetrohippocampal region76.511260986328168.3954238891602
211151sAMYStriatum-like amygdalar nuclei40.49639511108429.8610973358154
211151STRStriatum48.528766632080135.0802803039551
211151STRdStriatum dorsal region52.991306304931638.6868095397949
211151STRvStriatum ventral region45.46380996704131.4384651184082
211151THThalamus53.094032287597742.934154510498
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
91612GO:0006350IEAProcesstranscription
91612GO:0006355IEAProcessregulation of transcription, DNA-dependent
91612GO:0007275IEAProcessdevelopment
91612GO:0008270IEAFunctionzinc ion binding
91612GO:0016563IEAFunctiontranscriptional activator activity
91612GO:0045941IEAProcesspositive regulation of transcription
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
91612CHUR_HUMANQ8WUH1IPR009508ChurchillChurchill

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