Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:9230
Official Symbol:RAB11B
Other Aliases:H-YPT3|MGC133246
See related:HGNC:9761|MIM:604198|HPRD:05009
Chromosome:19
Location:19p13.2
Gene Description:RAB11B, member RAS oncogene family
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0389
ORGANISM:human
Entrez Gene ID:9230
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:12065639
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Frontal Cortex
Drug Effects:Downregulated
Fold Change:-1.2 :: -1.7 :: -1.6 :: -1.5 :: -1.5 :: -1.4
KARG Evidence 2
KARG ID:EVIM0457
ORGANISM:human
Entrez Gene ID:9230
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:12065639
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Motor Cortex
Drug Effects:Downregulated
Fold Change:1.1 :: -1 :: -1.2 :: -2 :: -1.2
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
9230GO:0000166IEAFunctionnucleotide binding
9230GO:0003924TASFunctionGTPase activity
9230GO:0005525IEAFunctionGTP binding
9230GO:0007264IEAProcesssmall GTPase mediated signal transduction
9230GO:0015031IEAProcessprotein transport
9230GO:0016020IEAComponentmembrane
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
-22841NP_055719.1RAB11 family interacting protein 2 (class I)HPRD10548
-10133NP_068815.2optineurinHPRD03891
NP_004209.1--Rip11HPRD05009
NP_004209.110133-OptineurinHPRD05009
NP_004209.19727NP_055515.1rab11-family interacting protein 3HPRD18521
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
9230RB11B_HUMANQ15907IPR013684Miro-likeMiro-like
9230RB11B_HUMANQ15907IPR013753RasRas
9230RB11B_HUMANQ15907IPR001806Ras_trnsfrmngRas GTPase
9230RB11B_HUMANQ15907IPR002078Sig54_interactSigma-54 factor, interaction region

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