Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:9314
Official Symbol:KLF4
Other Aliases:EZF|GKLF
See related:HGNC:6348|MIM:602253
Chromosome:9
Location:9q31
Gene Description:Kruppel-like factor 4 (gut)
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0580
ORGANISM:human
Entrez Gene ID:9314
Evidence Type:Mapping from rat
Evidence ID Type:Entrez Gene
Evidence ID:114505
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
9314GO:0003676IEAFunctionnucleic acid binding
9314GO:0003700ISSFunctiontranscription factor activity
9314GO:0003700NASFunctiontranscription factor activity
9314GO:0005634IEAComponentnucleus
9314GO:0005634ISSComponentnucleus
9314GO:0006350IEAProcesstranscription
9314GO:0007500TASProcessmesodermal cell fate determination
9314GO:0008270IEAFunctionzinc ion binding
9314GO:0008270ISSFunctionzinc ion binding
9314GO:0008270NASFunctionzinc ion binding
9314GO:0008285TASProcessnegative regulation of cell proliferation
9314GO:0016563ISSFunctiontranscriptional activator activity
9314GO:0016563NASFunctiontranscriptional activator activity
9314GO:0016564IEPFunctiontranscriptional repressor activity
9314GO:0016564ISSFunctiontranscriptional repressor activity
9314GO:0045892IEPProcessnegative regulation of transcription, DNA-dependent
9314GO:0045892ISSProcessnegative regulation of transcription, DNA-dependent
9314GO:0046872IEAFunctionmetal ion binding
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
AAH30811.1--p53HPRD03769
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
9314KLF4_HUMANO43474IPR000694PRO_richProline-rich region
9314KLF4_HUMANO43474IPR007087Znf_C2H2Zinc finger, C2H2-type
9314KLF4_HUMANO43474IPR007086Znf_C2H2_subZinc finger, C2H2-subtype

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