Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:9322
Official Symbol:TRIP10
Other Aliases:CIP4|HSTP|STOT|STP
See related:HGNC:12304|MIM:604504|HPRD:05142
Chromosome:19
Location:19p13.3
Gene Description:thyroid hormone receptor interactor 10
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0374
ORGANISM:human
Entrez Gene ID:9322
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:12065639
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Frontal Cortex
Drug Effects:Downregulated
Fold Change:-1.7 :: -1.8 :: -2.1 :: -2.1 :: -1.6 :: -1.5
KARG Evidence 2
KARG ID:EVIM0392
ORGANISM:human
Entrez Gene ID:9322
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:12065639
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Frontal Cortex
Drug Effects:Downregulated
Fold Change:-1.4 :: -1.8 :: -1.6 :: -1.8 :: -1.3 :: -1.4
KARG Evidence 3
KARG ID:EVIM0442
ORGANISM:human
Entrez Gene ID:9322
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:12065639
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Motor Cortex
Drug Effects:Downregulated
Fold Change:-1.1 :: -1.1 :: -1.3 :: -3.3 :: -1.6
KARG Evidence 4
KARG ID:EVIM0460
ORGANISM:human
Entrez Gene ID:9322
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:12065639
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Motor Cortex
Drug Effects:Downregulated
Fold Change:1 :: 1.1 :: -1.2 :: -2.2 :: -1.6
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
106628CBCerebellum2.266175746917722.40109181404114
106628CTXCerebral cortex14.73505687713629.15097713470459
106628HIPHippocampal region45.049179077148427.6391887664795
106628HPFHippocampal formation38.638217926025425.0348720550537
106628HYHypothalamus18.999048233032211.3632946014404
106628LSXLateral septal complex3.4804642200471.79327714443207
106628MBMidbrain9.563270568847667.16186094284058
106628MYMedulla13.684120178222710.2127485275269
106628OLFOlfactory bulb21.108171463012712.0548992156982
106628PPons9.960620880126957.94761896133423
106628PALPallidum13.1547641754158.3565502166748
106628RHPRetrohippocampal region29.695390701293920.8174877166748
106628sAMYStriatum-like amygdalar nuclei17.875518798828110.6891965866089
106628STRStriatum15.54414272308358.18998146057129
106628STRdStriatum dorsal region16.07487297058118.53119945526123
106628STRvStriatum ventral region19.46883583068858.97725868225098
106628THThalamus6.341914176940923.74224615097046
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
9322GO:0005515TASFunctionprotein binding
9322GO:0005737NASComponentcytoplasm
9322GO:0007165TASProcesssignal transduction
9322GO:0030036NASProcessactin cytoskeleton organization and biogenesis
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_004231.1--TR betaHPRD05142
NP_004231.1--TubulinHPRD05142
NP_004231.1--RICH-1HPRD05142
NP_004231.1--Pgamma rod(PDE6G)HPRD05142
NP_004231.123433NP_036381.1ras-like protein TC10HPRD05791
NP_004231.123433NP_036381.1ras-like protein TC10HPRD05142
NP_004231.155114NP_060524.4nadrin isoform 2HPRD12207
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
9322CIP4_HUMANQ15642IPR001060Cdc15_Fes_CIP4Cdc15/Fes/CIP4
9322CIP4_HUMANQ15642IPR001452SH3Src homology-3
9322CIP4_HUMANQ15642IPR011511SH3_2Variant SH3

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