Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:9341
Official Symbol:VAMP3
Other Aliases:CEB
See related:HGNC:12644|MIM:603657|HPRD:04711
Chromosome:1
Location:1p36.23
Gene Description:vesicle-associated membrane protein 3 (cellubrevin)
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0422
ORGANISM:human
Entrez Gene ID:9341
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:12065639
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Frontal Cortex
Drug Effects:Downregulated
Fold Change:-1.5 :: -1.9 :: 1.7 :: -1.9 :: -1.5 :: -1.6
KARG Evidence 2
KARG ID:EVIM0423
ORGANISM:human
Entrez Gene ID:9341
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:12065639
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Frontal Cortex
Drug Effects:Downregulated
Fold Change:-1.7 :: -1.2 :: -1.6 :: -1.6 :: -1.4 :: -1.4
KARG Evidence 3
KARG ID:EVIM0490
ORGANISM:human
Entrez Gene ID:9341
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:12065639
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Motor Cortex
Drug Effects:Downregulated
Fold Change:1.3 :: 1.3 :: -1.5 :: -3.1 :: -1.8
KARG Evidence 4
KARG ID:EVIM0491
ORGANISM:human
Entrez Gene ID:9341
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:12065639
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Motor Cortex
Drug Effects:Downregulated
Fold Change:1.1 :: -1.1 :: -1.2 :: -1.8 :: -1.2
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
22319CBCerebellum18.710313796997119.8366184234619
22319CTXCerebral cortex5.291020393371583.84315013885498
22319HIPHippocampal region4.47985267639164.25180673599243
22319HPFHippocampal formation4.147809505462653.66097474098206
22319HYHypothalamus1.66610920429231.16816639900208
22319LSXLateral septal complex6.806340217590334.65306949615479
22319MBMidbrain2.993716001510622.82238245010376
22319MYMedulla4.35138225555424.3474292755127
22319OLFOlfactory bulb10.29712867736827.71127080917358
22319PPons2.796564579010012.89202284812927
22319PALPallidum2.012307167053221.52422678470612
22319RHPRetrohippocampal region3.623394489288332.77073502540588
22319sAMYStriatum-like amygdalar nuclei0.5545035600662230.702560722827911
22319STRStriatum2.23498415946961.73180043697357
22319STRdStriatum dorsal region2.14451408386231.78806161880493
22319STRvStriatum ventral region2.109221935272221.25045597553253
22319THThalamus2.867530584335333.35022115707397
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
9341GO:0006461TASProcessprotein complex assembly
9341GO:0006904TASProcessvesicle docking during exocytosis
9341GO:0006944TASProcessmembrane fusion
9341GO:0016020IEAComponentmembrane
9341GO:0016021TASComponentintegral to membrane
9341GO:0019717IEAComponentsynaptosome
9341GO:0045202IEAComponentsynapse
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
-10134NP_005736.3B-cell receptor-associated protein 31HPRD02319
NP_004772.110134-BAP31HPRD04711
NP_004772.19744NP_055531.1centaurin beta1BIND183623
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
9341VAMP3_HUMANQ15836IPR001388SynaptobrevinSynaptobrevin

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