Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:9404
Official Symbol:LPXN
Other Aliases:LDPL
See related:HGNC:14061|MIM:605390|HPRD:05651
Chromosome:11
Location:11q12.1
Gene Description:leupaxin
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0305
ORGANISM:human
Entrez Gene ID:9404
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:15816859
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Prefrontal Cortex
Drug Effects:Downregulated
Fold Change:-0.58
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
107321CBCerebellum4.479649066925055.43173742294312
107321CTXCerebral cortex2.417024850845342.62359356880188
107321HIPHippocampal region1.193490743637081.32013618946075
107321HPFHippocampal formation1.339672684669491.43242263793945
107321HYHypothalamus0.3969099223613740.376971691846848
107321LSXLateral septal complex0.2057095915079120.170110538601875
107321MBMidbrain1.750501155853272.14393901824951
107321MYMedulla2.743995189666753.18853688240051
107321OLFOlfactory bulb1.732905983924871.40679526329041
107321PPons1.802435040473942.25883603096008
107321PALPallidum0.2697166502475740.522102057933807
107321RHPRetrohippocampal region1.641207456588751.61881077289581
107321sAMYStriatum-like amygdalar nuclei0.3773666620254520.510576903820038
107321STRStriatum0.5266642570495610.603781521320343
107321STRdStriatum dorsal region0.6140543818473820.687738120555878
107321STRvStriatum ventral region0.4692254066467290.576007783412933
107321THThalamus0.8245909810066220.827457427978516
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
9404GO:0005737NRComponentcytoplasm
9404GO:0006461TASProcessprotein complex assembly
9404GO:0007155NASProcesscell adhesion
9404GO:0007165TASProcesssignal transduction
9404GO:0008270IEAFunctionzinc ion binding
9404GO:0046872IEAFunctionmetal ion binding
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
9404LPXN_HUMANO60711IPR001781LIM_Zn_bdLIM, zinc-binding

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