Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:9411
Official Symbol:ARHGAP29
Other Aliases:PARG1|RP11-255E17.1
See related:HGNC:30207|HPRD:06674
Chromosome:1
Location:1p22.1
Gene Description:Rho GTPase activating protein 29
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0146
ORGANISM:human
Entrez Gene ID:9411
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:12629581
Addiction Drug:COCAINE
Addiction Drug Detail:COCAINE ABUSE
Addiction Brain Area:Dorsolateral Prefrontal Cortex
Drug Effects:Upregulated/Downregulated
Fold Change:3.28 :: 3.91 :: 2.52 :: 1.15 :: -4.37 :: -3.53 :: -4.74
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
214137CBCerebellum2.939566612243655.96272039413452
214137CTXCerebral cortex4.032968997955324.18122148513794
214137HIPHippocampal region3.848078727722177.23125457763672
214137HPFHippocampal formation2.758987188339234.78326892852783
214137HYHypothalamus1.52621769905091.57087016105652
214137LSXLateral septal complex2.238510131835941.81320691108704
214137MBMidbrain4.355221271514897.42232275009155
214137MYMedulla0.9388777017593381.62544012069702
214137OLFOlfactory bulb6.123700141906745.92745685577393
214137PPons0.6243177652359011.09537756443024
214137PALPallidum1.936236023902891.59950959682465
214137RHPRetrohippocampal region0.3534341454505920.408259570598602
214137sAMYStriatum-like amygdalar nuclei1.044990539550781.89728951454163
214137STRStriatum2.278999805450441.87505447864532
214137STRdStriatum dorsal region2.117472648620611.77842032909393
214137STRvStriatum ventral region3.304792881011962.20288443565369
214137THThalamus4.80563211441045.23137378692627
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
9411GO:0005100TASFunctionRho GTPase activator activity
9411GO:0007242IEAProcessintracellular signaling cascade
9411GO:0007266TASProcessRho protein signal transduction
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
9411IPR002219DAG_PE_bdProtein kinase C, phorbol ester/diacylglycerol binding
9411IPR000198RhoGAPRhoGAP

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