Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:9456
Official Symbol:HOMER1
Other Aliases:SYN47|Ves-1
See related:HGNC:17512|MIM:604798|HPRD:09211
Chromosome:5
Location:5q14.2
Gene Description:homer homolog 1 (Drosophila)
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0345
ORGANISM:human
Entrez Gene ID:9456
Evidence Type:Mapping from mouse
Evidence ID Type:Entrez Gene
Evidence ID:26556
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
26556CBCerebellum2.022114872932431.9254532456398
26556CTXCerebral cortex100.0100.0
26556HIPHippocampal region39.974500656127943.372537612915
26556HPFHippocampal formation48.275590896606446.7920913696289
26556HYHypothalamus4.64757901430133.02364137768745
26556LSXLateral septal complex36.560456275939923.175094127655
26556MBMidbrain3.894345223903662.94139754772186
26556MYMedulla8.886851310729986.17313694953918
26556OLFOlfactory bulb85.049354553222772.7956657409668
26556PPons8.397928953170785.99611532688141
26556PALPallidum9.070871829986576.90313315391541
26556RHPRetrohippocampal region63.5881137847950.7015113830566
26556sAMYStriatum-like amygdalar nuclei16.120429039001511.6565566062927
26556STRStriatum90.220600128173864.8516254425049
26556STRdStriatum dorsal region100.084.0811576843262
26556STRvStriatum ventral region79.479202270507855.4436283111572
26556THThalamus3.624438971281052.19168192148209
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
9456GO:0005515TASFunctionprotein binding
9456GO:0005887TASComponentintegral to plasma membrane
9456GO:0007206TASProcessmetabotropic glutamate receptor, phospholipase C activating pathway
9456GO:0007268TASProcesssynaptic transmission
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
-116986NP_055585.1centaurin, gamma 1HPRD05687
NP_004263.1--DNM3HPRD09211
NP_004263.1--TRPC1HPRD09211
NP_004263.1116986-Phosphoinositide 3 kinase enhancerHPRD09211
NP_004263.19456NP_004263.1homer 1HPRD09211
NP_004263.185461NP_203752.1TPR domain, ankyrin-repeat and coiled-coil-containingHPRD18146
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
9456HOME1_HUMANQ86YM7IPR000697EVH1EVH1

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