Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:952
Official Symbol:CD38
Other Aliases:T10
See related:HGNC:1667|MIM:107270|HPRD:00116
Chromosome:4
Location:4p15
Gene Description:CD38 molecule
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:QTL0090
ORGANISM:human
Entrez Gene ID:952
Evidence Type:QTL assay
Evidence ID Type:PUBMED
Evidence ID:NA
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
KARG Evidence 2
KARG ID:QTL0091
ORGANISM:human
Entrez Gene ID:952
Evidence Type:QTL assay
Evidence ID Type:PUBMED
Evidence ID:NA
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
KARG Evidence 3
KARG ID:QTL0092
ORGANISM:human
Entrez Gene ID:952
Evidence Type:QTL assay
Evidence ID Type:PUBMED
Evidence ID:NA
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
KARG Evidence 4
KARG ID:QTL0093
ORGANISM:human
Entrez Gene ID:952
Evidence Type:QTL assay
Evidence ID Type:PUBMED
Evidence ID:NA
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
12494CBCerebellum1.113314151763921.61900019645691
12494CTXCerebral cortex0.3731706142425540.54507702589035
12494HIPHippocampal region0.286457955837250.47864505648613
12494HPFHippocampal formation0.3290004432201390.607871413230896
12494HYHypothalamus0.3091098368167880.385168641805649
12494LSXLateral septal complex0.648546218872070.971585810184479
12494MBMidbrain0.3273943662643430.72232574224472
12494MYMedulla0.4658011198043820.96289986371994
12494OLFOlfactory bulb0.706617355346680.604205906391144
12494PPons0.3737071752548220.558558106422424
12494PALPallidum0.3600856363773350.505639910697937
12494RHPRetrohippocampal region0.4103474020957950.814497590065002
12494sAMYStriatum-like amygdalar nuclei0.3565206527709960.519559919834137
12494STRStriatum0.3345739841461180.45277327299118
12494STRdStriatum dorsal region0.2782882452011110.397192269563675
12494STRvStriatum ventral region0.3710986971855160.367471039295197
12494THThalamus0.5612052679061890.817346453666687
KARG Evidence 5
KARG ID:QTL0090
Trait:alcohol preference locus, female specific
Peak:26
Peak Marker:D5Mit11
Parents:recombinant Inbreds(RI) AXB and BXA
Evidence ID:9880655
KARG Evidence 6
KARG ID:QTL0091
Trait:alcohol preference locus, male specific
Peak:26
Peak Marker:D5Mit11
Parents:recombinant Inbreds(RI) AXB and BXA
Evidence ID:9880655
KARG Evidence 7
KARG ID:QTL0092
Trait:METH responses for climbing
Peak:26
Peak Marker:D5Rik85
Parents:C57BL/6J x DBA/2J intercross
Evidence ID:8987796
KARG Evidence 8
KARG ID:QTL0093
Trait:Acute ethanol sensitivity
Peak:26
Peak Marker:NA
Parents:C57BL/6J x DBA/2J intercross
Evidence ID:11003198
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
952GO:0003953IEAFunctionNAD+ nucleosidase activity
952GO:0004872IEAFunctionreceptor activity
952GO:0005624TASComponentmembrane fraction
952GO:0005886TASComponentplasma membrane
952GO:0006091NRProcessgeneration of precursor metabolites and energy
952GO:0007165NASProcesssignal transduction
952GO:0008624TASProcessinduction of apoptosis by extracellular signals
952GO:0016021IEAComponentintegral to membrane
952GO:0016787IEAFunctionhydrolase activity
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_001766.15175NP_000433.2platelet/endothelial cell adhesion molecule (CD31 antigen)HPRD00116
NP_001766.12214NP_000560.3Fc fragment of IgG, low affinity IIIa, receptor for (CD16)HPRD00116
NP_001766.12214NP_000560.3Fc fragment of IgG, low affinity IIIa, receptor for (CD16)HPRD00903
NP_001766.13932NP_005347.2lymphocyte-specific protein tyrosine kinaseHPRD00116
NP_001766.13932NP_005347.2lymphocyte-specific protein tyrosine kinaseHPRD01080
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
952CD38_HUMANP28907IPR003193Rib_hydrolayseADP-ribosyl cyclase (CD38/157)

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