Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:9575
Official Symbol:CLOCK
Other Aliases:KIAA0334
See related:HGNC:2082|MIM:601851|HPRD:03508
Chromosome:4
Location:4q12
Gene Description:clock homolog (mouse)
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0339
ORGANISM:human
Entrez Gene ID:9575
Evidence Type:Mapping from mouse
Evidence ID Type:Entrez Gene
Evidence ID:12753
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
12753CBCerebellum5.045044541358954.41852509975433
12753CTXCerebral cortex6.384466409683233.85828086733818
12753HIPHippocampal region37.061815261840822.7237319946289
12753HPFHippocampal formation25.377195358276415.0762805938721
12753HYHypothalamus3.120844066143041.84093694388866
12753LSXLateral septal complex6.055558592081073.68255676329136
12753MBMidbrain3.127609342336652.34792572259903
12753MYMedulla8.871913790702828.61651402711868
12753OLFOlfactory bulb13.09670925140387.31472444534302
12753PPons8.254026710987097.2011359333992
12753PALPallidum2.450623258948331.64257156848907
12753RHPRetrohippocampal region9.398506879806526.17049199342728
12753sAMYStriatum-like amygdalar nuclei2.600541844964031.37340889126062
12753STRStriatum4.776578262448312.63387380540371
12753STRdStriatum dorsal region4.245376519858842.29708903282881
12753STRvStriatum ventral region7.757884562015534.09260120987892
12753THThalamus4.799044966697693.16058972477913
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
9575GO:0003700TASFunctiontranscription factor activity
9575GO:0004871IEAFunctionsignal transducer activity
9575GO:0005634IEAComponentnucleus
9575GO:0006357TASProcessregulation of transcription from RNA polymerase II promoter
9575GO:0007165TASProcesssignal transduction
9575GO:0007623TASProcesscircadian rhythm
9575GO:0009648TASProcessphotoperiodism
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_004889.1--PER3HPRD03508
NP_004889.156938NP_064568.3aryl hydrocarbon receptor nuclear translocator-like 2HPRD16507
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
9575CLOCK_HUMANO15516IPR001092HLH_basicBasic helix-loop-helix dimerisation region bHLH
9575CLOCK_HUMANO15516IPR001067Nuc_translocatNuclear translocator
9575CLOCK_HUMANO15516IPR000014PASPAS
9575CLOCK_HUMANO15516IPR013655PAS_3PAS fold-3
9575CLOCK_HUMANO15516IPR013767PAS_foldPAS fold

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