Knowledgebase for Addiction-Related Genes
Home | Score | Chromosome | Pathway | Advanced Search | BLAST Search | Downloads | Publications | FAQ & Help |   

KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:9588
Official Symbol:PRDX6
Other Aliases:1-Cys|AOP2|KIAA0106|MGC46173|NSGPx|PRX|aiPLA2|p29
See related:HGNC:16753|MIM:602316|HPRD:03817
Chromosome:1
Location:1q25.1
Gene Description:peroxiredoxin 6
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0373
ORGANISM:human
Entrez Gene ID:9588
Evidence Type:Mapping from rat
Evidence ID Type:Entrez Gene
Evidence ID:94167
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
KARG Evidence 2
KARG ID:EVIP0196
ORGANISM:human
Entrez Gene ID:9588
Evidence Type:Proteomics
Evidence ID Type:PUBMED
Evidence ID:15542695
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Whole Brain
Drug Effects:Upregulated
Fold Change:3.10
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
320769CBCerebellum11.540149271488219.0814878940582
11758CBCerebellum16.018079757690444.2382850646973
11758CTXCerebral cortex6.068921566009525.73617219924927
320769CTXCerebral cortex9.416341841220867.03803125023842
11758HIPHippocampal region21.288753509521525.0992412567139
320769HIPHippocampal region7.497780583798899.07116867601871
11758HPFHippocampal formation20.339813232421922.2903423309326
320769HPFHippocampal formation6.698280878365047.21558622270823
11758HYHypothalamus3.014646291732794.09713840484619
320769HYHypothalamus6.975903898477556.93534132838249
320769LSXLateral septal complex3.173599779605873.13515043258667
11758LSXLateral septal complex6.081225395202646.40559482574463
11758MBMidbrain5.5952587127685510.0087442398071
320769MBMidbrain6.369645819067966.21797598898411
320769MYMedulla12.046520441770612.3643750995398
11758MYMedulla7.260644435882579.6305685043335
11758OLFOlfactory bulb29.948898315429728.6953411102295
320769OLFOlfactory bulb9.248201906681068.33793342113495
11758PPons6.5837745666503910.5225553512573
320769PPons8.4765227958568.66590333729982
11758PALPallidum4.247939109802254.67323732376099
320769PALPallidum5.186160877346994.57922561466694
11758RHPRetrohippocampal region18.313848495483418.1768627166748
320769RHPRetrohippocampal region5.009798023849734.15412532538176
11758sAMYStriatum-like amygdalar nuclei23.572113037109417.7475490570068
320769sAMYStriatum-like amygdalar nuclei6.645555552095174.66809744015336
11758STRStriatum15.985527038574214.2572336196899
320769STRStriatum6.374696195125584.77394624054432
11758STRdStriatum dorsal region15.913842201232915.3137884140015
320769STRdStriatum dorsal region6.769165985286245.1057870015502
11758STRvStriatum ventral region13.74922466278089.42446708679199
320769STRvStriatum ventral region7.074718177318574.68016013503075
320769THThalamus10.02108182013038.28303393721581
11758THThalamus5.258304595947277.55641937255859
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
9588GO:0004601IEAFunctionperoxidase activity
9588GO:0004623IDAFunctionphospholipase A2 activity
9588GO:0005764IEAComponentlysosome
9588GO:0005829NASComponentcytosol
9588GO:0006979IDAProcessresponse to oxidative stress
9588GO:0009395IDAProcessphospholipid catabolism
9588GO:0016042IEAProcesslipid catabolism
9588GO:0016491IEAFunctionoxidoreductase activity
9588GO:0016787IEAFunctionhydrolase activity
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_004896.19588NP_004896.1peroxiredoxin 6HPRD03817
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
9588PRDX6_HUMANP30041IPR000866AhpC-TSAAlkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen
9588PRDX6_HUMANP30041IPR013740RedoxinRedoxin

© Center for Bioinformatics(CBI), Peking University
Any Comments and suggestions to : KARG GROUP.