Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:9607
Official Symbol:CART
Other Aliases:-
See related:MIM:602606|HPRD:04006
Chromosome:5
Location:5q13.2
Gene Description:cocaine- and amphetamine-regulated transcript
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0066
ORGANISM:human
Entrez Gene ID:9607
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:15009677
Addiction Drug:COCAINE
Addiction Drug Detail:COCAINE ABUSE
Addiction Brain Area:Nucleus Accumbens
Drug Effects:Upregulated
Fold Change:0.09 :: -0.12 :: 0.62 :: 1.12 :: 0.39 :: 0.38 :: -0.10 :: 0.67 :: 0.40 :: 0.79
KARG Evidence 2
KARG ID:EVIM1142
ORGANISM:human
Entrez Gene ID:9607
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:12716423
Addiction Drug:COCAINE
Addiction Drug Detail:COCAINE ABUSE
Addiction Brain Area:Ventral Tegmental Area
Drug Effects:Downregulated
Fold Change:-
KARG Evidence 3
KARG ID:EVID0002
ORGANISM:human
Entrez Gene ID:9607
Evidence Type:Database Annotations
Evidence ID Type:OMIM
Evidence ID:MIM:113505
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
27220CBCerebellum7.39330436289318.71752217411995
27220CTXCerebral cortex10.55407309532179.86579418182373
27220HIPHippocampal region3.922655940055854.62305903434753
27220HPFHippocampal formation6.553183078765876.37618815898895
27220HYHypothalamus22.765132904052737.8216257095337
27220LSXLateral septal complex19.244468212127727.9244890213013
27220MBMidbrain9.4015083312988312.0631132125854
27220MYMedulla8.670913219451914.1103978157043
27220OLFOlfactory bulb26.238934516906731.8210096359253
27220PPons4.962609171867376.40947532653809
27220PALPallidum17.666500568389929.2953481674194
27220RHPRetrohippocampal region11.19042336940779.03301155567169
27220sAMYStriatum-like amygdalar nuclei25.222669601440437.9794263839722
27220STRStriatum16.928405284881622.3328886032104
27220STRdStriatum dorsal region2.194275677204132.15801745653152
27220STRvStriatum ventral region62.276807785034275.5901145935059
27220THThalamus4.90583240985876.29298675060272
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
9607GO:0005615TASComponentextracellular space
9607GO:0007165TASProcesssignal transduction
9607GO:0007218IEAProcessneuropeptide signaling pathway
9607GO:0007267TASProcesscell-cell signaling
9607GO:0007268IEAProcesssynaptic transmission
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
9607CART_HUMANQ16568IPR009106CARTCART satiety factor

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