Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:9638
Official Symbol:FEZ1
Other Aliases:-
See related:HGNC:3659|MIM:604825|HPRD:09212
Chromosome:11
Location:11q24.2
Gene Description:fasciculation and elongation protein zeta 1 (zygin I)
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0347
ORGANISM:human
Entrez Gene ID:9638
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:15816859
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Nucleus Accumbens
Drug Effects:Downregulated
Fold Change:-0.67
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
235180CBCerebellum100.0100.0
235180CTXCerebral cortex100.0100.0
235180HIPHippocampal region100.0100.0
235180HPFHippocampal formation100.0100.0
235180HYHypothalamus100.0100.0
235180LSXLateral septal complex100.0100.0
235180MBMidbrain100.0100.0
235180MYMedulla100.0100.0
235180OLFOlfactory bulb100.0100.0
235180PPons100.0100.0
235180PALPallidum100.0100.0
235180RHPRetrohippocampal region100.0100.0
235180sAMYStriatum-like amygdalar nuclei100.0100.0
235180STRStriatum100.0100.0
235180STRdStriatum dorsal region100.0100.0
235180STRvStriatum ventral region100.0100.0
235180THThalamus100.0100.0
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
9638GO:0005515IPIFunctionprotein binding
9638GO:0007155TASProcesscell adhesion
9638GO:0007399TASProcessnervous system development
9638GO:0007411TASProcessaxon guidance
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
-10519NP_006375.1calcium and integrin binding 1 (calmyrin)HPRD03800
-27185NP_061132.1disrupted in schizophrenia 1HPRD05553
NP_005094.110519-Calcium and integrin binding proteinHPRD09212
NP_005094.127185-DISC1HPRD09212
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
9638FEZ1_HUMANQ99689IPR011680FEZFEZ-like

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