Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:9973
Official Symbol:CCS
Other Aliases:MGC138260
See related:HGNC:1613|MIM:603864|HPRD:04841
Chromosome:11
Location:11q13
Gene Description:copper chaperone for superoxide dismutase
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:QTL0250
ORGANISM:human
Entrez Gene ID:9973
Evidence Type:QTL assay
Evidence ID Type:PUBMED
Evidence ID:NA
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
12460CBCerebellum0.00.0
12460CTXCerebral cortex0.00.0
12460HIPHippocampal region0.00.0
12460HPFHippocampal formation0.00.0
12460HYHypothalamus0.00.0
12460LSXLateral septal complex0.00.0
12460MBMidbrain0.00.0
12460MYMedulla0.00.0
12460OLFOlfactory bulb0.00.0
12460PPons0.00.0
12460PALPallidum0.00.0
12460RHPRetrohippocampal region0.00.0
12460sAMYStriatum-like amygdalar nuclei0.00.0
12460STRStriatum0.00.0
12460STRdStriatum dorsal region0.00.0
12460STRvStriatum ventral region0.00.0
12460THThalamus0.00.0
KARG Evidence 2
KARG ID:QTL0250
Trait:Chronic ethanol withdrawal
Peak:4
Peak Marker:D19Mit109
Parents:B6D2F2 (C57BL/6J x DBA/2J)
Evidence ID:11919667
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
9973GO:0004785IEAFunctioncopper, zinc superoxide dismutase activity
9973GO:0005375TASFunctioncopper ion transporter activity
9973GO:0005507TASFunctioncopper ion binding
9973GO:0005625TASComponentsoluble fraction
9973GO:0005737NRComponentcytoplasm
9973GO:0006457IEAProcessprotein folding
9973GO:0006801TASProcesssuperoxide metabolism
9973GO:0008270IEAFunctionzinc ion binding
9973GO:0015680TASProcessintracellular copper ion transport
9973GO:0030001IEAProcessmetal ion transport
9973GO:0046872IEAFunctionmetal ion binding
9973GO:0051082IEAFunctionunfolded protein binding
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
9973CCS_HUMANO14618IPR006121HeavyMe_transptHeavy metal transport/detoxification protein
9973CCS_HUMANO14618IPR001802HG_scavengerMercury scavenger protein
9973CCS_HUMANO14618IPR001424SOD_Cu_ZnSuperoxide dismutase, copper/zinc binding

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