Knowledgebase for Addiction-Related Genes
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KARG >> Publications Integrated in KARG Database
Our list of publications included recent review papers on addiction selected from results of PUBMED query '(addiction OR "drug abuse") AND review' as well as research papers selected from PubMed query '(addiction OR "drug abuse") AND (gene OR microarray OR proteomics OR QTL OR "population association" OR "genetic linkage")'. KARG 2.0 further included papers selected from PubMed query '("addiction" OR "abuse*") AND (genetic* AND association*)'. We probably cannot claim that our collection represents "all" of the publications with addiction genes, but we are confident that our collection is by far the most comprehensive to date.

PUBMED IDTitleFirst AuthorPub Time
10064377Does the short variant of the serotonin transporter linked polymorphic region constitute a marker of alcohol dependenceHammoumi S1999
10235270Genetic association between alcohol withdrawal symptoms and polymorphism of CCK gene promoterOkubo T1999
10483044No association between the serotonin transporter promoter region (5-HTTLPR) and the dopamine D3 receptor (BalI D3DR) polymorphisms and heroin addictionKotler M1999
10673776DRD4 exon III VNTR polymorphism-susceptibility factor for heroin dependence? Results of a case-control and a family-based association approachFranke P2000
10817597Association of the N-acetyltransferase I gene (NATI) with mild and severe substance abuseComings DE2000
10822338No association between (AAT)n repeats in the cannabinoid receptor gene (CNR1) and heroin abuse in a Chinese populationLi T2000
10881204Reappraisal of the association between the DRD2 gene, alcoholism and addictionGorwood P2000
10888062An abundant proneurotensin polymorphism, 479A>G, and a test of its association with alcohol dependence in a Finnish populationVanakoski J2000
11054765The D(2) dopamine receptor A(1) allele and opioid dependence: association with heroin use and response to methadone treatmentLawford BR2000
11054768Association analysis of polymorphisms in the DRD4 gene and heroin abuse in Chinese subjectsLi T2000
11054777Human dopamine transporter gene: coding region conservation among normal, Tourette's disorder, alcohol dependence and attention-deficit hyperactivity disorder populations.Vendenbergh DJ2000
11236836Genetic determinants of alcohol addiction and metabolism: a survey in ItalyPastorelli R2001
11368834No association of CCK and CCK(B) receptor polymorphisms with alcohol dependence.Vanakoski J2001
11410714No association between the dopamine d2 receptor taqi a1 allele and earlier age of onset of alcohol dependence according to different specified criteriaAnghelescu I2001
11424981Nonreplication of association between mu-opioid-receptor gene (OPRM1) A118G polymorphism and substance dependenceFranke P2001
11509018Cholecystokinin (CCK) gene as a possible risk factor for smoking: a replication in two independent samplesComings DE2001
11840318A functional polymorphism within the mu-opioid receptor gene and risk for abuse of alcohol and other substancesSchinka JA2002
11857587Serotonin transporter promoter polymorphism, peripheral indexes of serotonin function, and personality measures in families with alcoholismStoltenberg SF2002
11920858Allelic association analysis of the dopamine D2, D3, 5-HT2A, and GABA(A)gamma2 receptors and serotonin transporter genes with heroin abuse in Chinese subjectsLi T2002
11927842No association between functional catechol O-methyl transferase 1947A>G polymorphism and smoking initiation, persistent smoking or smoking cessationDavid SP2002
11992566Potentially functional polymorphism in the promoter region of prodynorphin gene may be associated with protection against cocaine dependence or abuseChen AC2002
12022963Association study of novel human serotonin 5-HT(1B) polymorphisms with alcohol dependence in Taiwanese HanSun HF2002
12116270Relationship of the delta-opioid receptor gene to heroin abuse in a large Chinese case/control sampleXu K2002
12544000NPY Leu7Pro and alcohol dependence in Finnish and Swedish populationsZhu GS2003
12563176Monoamine oxidase polymorphisms and smoking behaviour in JapaneseIto H2003
12658362Association study of the dopamine and serotonin transporter genetic polymorphisms and methamphetamine abuse in Chinese malesHong CJ2003
12811641Dopamine D2 (DAD2) and dopamine D3 (DAD3) receptor gene polymorphisms and treatment outcome in alcohol dependenceWiesbeck GA2003
1355337Genetic vulnerability to drug abuse. The D2 dopamine receptor Taq I B1 restriction fragment length polymorphism appears more frequently in polysubstance abusersSmith SS1992
14569258Gender-specific contribution of the GABA(A) subunit genes on 5q33 in methamphetamine use disorderLin SK2003
14643564The A1 allele of the DRD2 gene (TaqI A polymorphisms) is associated with antisocial personality in a sample of alcohol-dependent patientsPonce G2003
15037869Substantial attributable risk related to a functional mu-opioid receptor gene polymorphism in association with heroin addiction in central SwedenBart G2004
15066703Polymorphisms of the dopamine D2 receptor, serotonin transporter, and GABA(A) receptor beta(3) subunit genes and alcoholism in Mexican-AmericansKonishi T2004
15077008Nicotine dependence in a prospective population-based study of adolescents: the protective role of a functional tyrosine hydroxylase polymorphismAnney RJ2004
15084894Possible interaction of alcohol dehydrogenase and aldehyde dehydrogenase genes with the dopamine D2 receptor gene in anxiety-depressive alcohol dependenceHuang SY2004
15091313DAT polymorphism and diverse clinical manifestations in methamphetamine abusersLiu HC2004
15184239Association of specific haplotypes of D2 dopamine receptor gene with vulnerability to heroin dependence in 2 distinct populationsXu K2006
15274053Association analysis of the DRD4 and COMT genes in methamphetamine abuseLi T2004
15289816Human cannabinoid receptor 1: 5' exons, candidate regulatory regions, polymorphisms, haplotypes and association with polysubstance abuseZhang PW2004
15459944Association study between brain-derived neurotrophic factor gene polymorphisms and methamphetamine abusers in JapanItoh K2005
15492764Dopamine receptor DRD2 genotype and smoking cessation outcome following treatment with bupropion SRSwan GE2005
15525999Increased attributable risk related to a functional mu-opioid receptor gene polymorphism in association with alcohol dependence in central SwedenBart G2005
15542696No association found between the type 1 sigma receptor gene polymorphisms and methamphetamine abuse in the Japanese population: a collaborative study by the Japanese Genetics Initiative for Drug AbuseInada T2004
15542697No association is found between the candidate genes of t-PA/plasminogen system and Japanese methamphetamine-related disorder: a collaborative study by the Japanese Genetics Initiative for Drug AbuseIwata N2004
15542732Gene polymorphisms of the mu opioid receptor in methamphetamine abusersIde S2004
15547445Association study of brain-derived neurotrophic factor gene polymorphism and alcoholismMatsushita S2004
15564898Association analysis of dopamine D2-like receptor genes and methamphetamine abuseChen CK2004
15608558Redefinition of the human kappa opioid receptor gene (OPRK1) structure and association of haplotypes with opiate addictionYuferov V2004
15608559The human serotonin receptor 2B: coding region polymorphisms and association with vulnerability to illegal drug abuseLin Z2004
15630072Haplotype-based localization of an alcohol dependence gene to the 5q34 {gamma}-aminobutyric acid type A gene clusterRadel M2005
15666411Human brain derived neurotrophic factor (BDNF) genes, splicing patterns, and assessments of associations with substance abuse and Parkinson's DiseaseLiu QR2005
15704216Association between the DRD2 A1 allele and opium addiction in the Iranian populationShahmoradgoli Najafabadi M2005
15721218A nonsynonymous polymorphism in the human fatty acid amide hydrolase gene did not associate with either methamphetamine dependence or schizophreniaMorita Y2005
15729709A functional glutathione S-transferase P1 gene polymorphism is associated with methamphetamine-induced psychosis in Japanese population.Hashimoto T2005
15731118Joint analysis of the NACP-REP1 marker within the alpha synuclein gene concludes association with alcohol dependenceB?nsch D2005
15770103Thr105Ile, a functional polymorphism of histamine N-methyltransferase, isOroszi GNA
15806583Association of the serotonin transporter promoter polymorphism with smoking behavior among adolescentsGerra G2005
15936534The X-box binding protein 1 (XBP1) gene is not associated with methamphetamine dependenceMorita Y2005
15955630Genotype combinations for monoamine oxidase-B intron 13 polymorphism and dopamine D2 receptor TaqIB polymorphism are associated with ever-smoking status among menCosta-Mallen P2005
16109452Brain-derived neurotrophic factor (Val66Met) genetic polymorphism is associated with substance abuse in malesCheng CY2005
16184603Confirmation of the association between a polymorphism in the promoter region of the prodynorphin gene and cocaine dependenceDahl JP2005
16314758Association of a polymorphism in the Homer1 gene with cocaine dependence in an African American populationDahl JP2006
16314761A functional prodynorphin promoter polymorphism and opioid dependenceRay R2005
16314880(AAT)n repeat in the cannabinoid receptor gene (CNR1): association with cocaine addiction in an African-Caribbean populationBallon N2006
16344719Association analysis of polymorphisms in serotonin 1B receptor (HTR1B) gene with heroin addiction: a comparison of molecular and statistically estimated haplotypesProudnikov D2006
16402083Linkage disequilibrium and association with methamphetamine dependence/psychosis of mu-opioid receptor gene polymorphismsIde S2006
16526025MAOA-uVNTR polymorphism in a Brazilian sample: further support for the association with impulsive behaviors and alcohol dependenceContini V2006
16529859Genetic variant of prodynorphin gene is risk factor for methamphetamine dependenceNomura A2006
16537431A dopamine transporter gene functional variant associated with cocaine abuse in a Brazilian sampleGuindalini C2006
16550213Genetic association of the human corticotropin releasing hormone receptor 1 (CRHR1) with binge drinking and alcohol intake patterns in two independent samplesTreutlein J2006
16594948Association between dopamine receptor D1 A-48G polymorphism and methamphetamine abuseLiu HC2006
16691130Influence of the serotonin transporter gene on comorbid disorders among alcohol-dependent individualsFrancine Z.C2006
16741914Association analysis of delta-opioid receptor gene polymorphisms in methamphetamine dependence/psychosisKobayashi H2006
16741937Association study of the CNR1 gene exon 3 alternative promoter region polymorphisms and substance dependenceHerman AI2006
16917946Cannabis receptor haplotype associated with fewer cannabis dependence symptoms in adolescentsHopfer CJ2006
16930369A genetic association study of dopamine metabolism-related genes and chronic headache with drug abuseCevoli S2006
16950574Association of THR105Ile, a functional polymorphism of histamine N-methyltransferase (HNMT), with alcoholism in German CaucasiansReuter M2007
16972078The fatty acid amide hydrolase 385 A/A (P129T) variant: haplotype analysis of an ancient missense mutation and validation of risk for drug addictionFlanagan JM2006
17067345Glutamate decarboxylase genes and alcoholism in Han Taiwanese menLoh el-W2006
17069991Test of association between TaqIA A1 allele and alcohol use disorder phenotypes in a sample of adolescent patients with serious substance and behavioral problems.Sakai JT2007
17083333Alcoholism is associated with GALR3 but not two other galanin receptor genesBelfer I2007
17106427Human clock, PER1 and PER2 polymorphisms: lack of association with cocaine dependence susceptibility and cocaine-induced paranoiaMalison RT2006
17157823Effect of mu-opioid receptor gene polymorphisms on heroin-induced subjective responses in a Chinese populationZhang D2007
17186223Association of the met66 allele of brain-derived neurotrophic factor (BDNF) with smokingLang UE2007
17189959Involvement of cannabinoid CB2 receptor in alcohol preference in mice and alcoholism in humansIshiguro H2007
17200667Nucleotide sequence variation within the human tyrosine kinase B neurotrophin receptor gene: association with antisocial alcohol dependenceK?Xu2007
17264803Dopamine transporter polymorphisms are associated with short-term response to smoking cessation treatmentO'Gara C2007
17284169RhoA, encoding a Rho GTPase, is associated with smoking initiationChen X2007
17290447The fatty acid amide hydrolase C385A (P129T) missense variant in cannabis users: studies of drug use and dependence in CaucasiansTyndale RF2007
17440936Association analysis of GABA receptor subunit genes on 5q33 with heroin dependence in a Chinese male populationLoh EW2007
17608938Variation in the gene coding for the M5 muscarinic receptor (CHRM5) influences cigarette dose but is not associated with dependence to drugs of addiction:evidence from a prospective population based cohort study of young adults.Anney RJ2007
17621164Association study between alcoholism and endocannabinoid metabolic enzyme genes encoding fatty acid amide hydrolase and monoglyceride lipase in a Japanese populationIwasaki S2007
17621168Association analysis of GRK3 gene promoter variants in cocaine abuseGuindalini C2007
17624982Variation in a bicarbonate co-transporter gene family member SLC4A7 is associated with propensity to addictions: a study using fine-mapping and three samplesIshiguro H2007
17671965Polymorphisms TaqI A of the DRD2, BalI of the DRD3, exon III repeat of the DRD4, and 3' UTR VNTR of the DAT: association with childhood ADHD in male African-Caribbean cocaine dependents?Ballon N2007
17804423Neurexin 3 polymorphisms are associated with alcohol dependence and altered expression of specific isoformsHishimoto A2007
18043764Association of alpha4beta2 nicotinic receptor and heavy smoking in schizophreniaVoineskos S2007
18058350DRD2/ANKK1 TaqI polymorphism and smoking behavior of Egyptian male cigarette smokersRadwan GN2007
18173840Dopamine-beta hydroxylase polymorphism and cocaine addictionGuindalini C2008
18181266A118g polymorphism in mu opioid receptor gene (oprm1): association with opiate addiction in subjects of Indian originKapur S2007
18184800Opioid neuropeptide genotypes in relation to heroin abuse: dopamine tone contributes to reversed mesolimbic proenkephalin expressionNikoshkov A2008
18307984Genetic association of DRD2 polymorphisms with anxiety scores among alcohol-dependent patientsJoe KH2008
7485245Preliminary evidence for an association of a dinucleotide repeat polymorphism at the MAOA gene with early onset alcoholism/substance abuseVanyukov MM1995
7573171DRD4 dopamine receptor genotype and CSF monoamine metabolites in Finnish alcoholics and controlsAdamson MD1995
7918698Dopamine D2-receptor gene polymorphisms in Scandinavian chronic alcoholicsGeijer T1994
8033754The dopamine D2 receptor gene: a genetic risk factor in substance abuseComings DE1994
8102114Dopamine D2 receptor RFLPs, haplotypes and their association with substance use in black and Caucasian research volunteersO'Hara BF1993
8488955DRD2 dopamine receptor genotype, linkage disequilibrium, and alcoholism in American Indians and other populationsGoldman D1993
8825889Lack of association between alcohol-dependence and D3 dopamine receptor gene in three independent samplesGorwood P1995
8873216Increased prevalence of the Taq I A1 allele of the dopamine receptor gene (DRD2) in obesity with comorbid substance use disorder: a preliminary reportBlum K1996
8907305Allele-specific PCR for simultaneous amplification of both alleles of a deletion polymorphism in intron 6 of the human dopamine 2 receptor gene (DRD2)Finckh U1996
9106242Cannabinoid receptor gene (CNR1): association with i.v. drug useComings DE1997
9129710Dopamine D2 receptor gene and alcoholism among four aboriginal groups and Han in TaiwanChen WJ1997
9152990Excess dopamine D4 receptor (D4DR) exon III seven repeat allele in opioid-dependent subjectsKotler M1997
9259374Linkage and association of a functional DRD2 variant [Ser311Cys] and DRD2 markers to alcoholism, substance abuse and schizophrenia in Southwestern American IndiansGoldman D1999
9322237Association analysis of the dopamine D4 gene exon III VNTR and heroin abuse in Chinese subjectsLi T1997
9399694Mu opioid receptor gene variants: lack of association with alcohol dependenceBergen AW1997
9491813Correlation of length of VNTR alleles at the X-linked MAOA gene and phenotypic effect in Tourette syndrome and drug abuseGade R1998
9583233An association between a microsatellite polymorphism at the DRD5 gene and the liability to substance abuse: pilot studyVanyukov MM1998
9702742Homozygosity at the dopamine D3 receptor gene is associated with opiate dependenceDuaux E1998
9756053Association of alcohol or other drug dependence with alleles of the mu opioid receptor gene (OPRM1)Kranzler HR1998
107447Evidence for the absence of a mutagenic effect of methadone in germ cells of Drosophila melanogaster.Zimmering S1979 Feb
158518Genetic screening of compounds used in drug abuse treatment. I. Naltrexone hydrochloride.Brusick D1978
510177The genetic interface of addiction.Ginsburg BE1979 Jan-Mar
558580A bioanthropological overview of addiction.Jonas DF1977 Spring
1096556Genetic determinants of alcohol addiction.Goodwin DW1975
1328660The neurotoxin 1-methyl-4-phenylpyridinium: a selective cytostatic agent in small-cell lung cancer cell lines with neuroendocrine properties.Marini AM1992 Oct 21
1337927Organization and expression of the gene encoding chick kainate binding protein, a member of the glutamate receptor family.Gregor P1992 Dec
1355337Genetic vulnerability to drug abuse. The D2 dopamine receptor Taq I B1 restriction fragment length polymorphism appears more frequently in polysubstance abusers.Smith SS1992 Sep
1363329Neurotransmitter transporter family cDNAs in a rat midbrain library: 'orphan transporters' suggest sizable structural variations.Uhl GR1992 Dec
1372443Preproenkephalin promoter "cassette" confers brain expression and synaptic regulation in transgenic mice.Donovan DM1992 Mar 15
1381123Neurotransmitter transporters (plus): a promising new gene family.Uhl GR1992 Jul
1471756Low platelet gamma-aminobutyrate aminotransferase and monoamine oxidase activities in chronic alcoholic patients.Sherif F1992 Dec
1476417[Haptoglobin polymorphism--not only a genetic marker]Lange V1992 Dec
1478653Human dopamine transporter gene (DAT1) maps to chromosome 5p15.3 and displays a VNTR.Vandenbergh DJ1992 Dec
1491719Regulation of gene expression by dopamine: implications in drug addiction.Conneely OM1992
1515577Expression of a single dopamine transporter cDNA can confer two cocaine binding sites.Boja JW1992 Mar
1531356Regulation of cyclic AMP response element-binding protein (CREB) phosphorylation by acute and chronic morphine in the rat locus coeruleus.Guitart X1992 Mar
1630603Cholecystokinin (CCK)-like material and CCK mRNA levels in the rat brain and spinal cord after acute or repeated morphine treatment.Pohl M1992 Mar
1631058Regulation of immediate early gene expression and AP-1 binding in the rat nucleus accumbens by chronic cocaine.Hope B1992 Jul 1
1650871[Molecular neurobiological research in the fight against drug abuse]Terenius L1991 Jul 24
1674558[Genetic factors and smoking habits]Yamaguchi E1991 Feb
1676593Human T-cell leukemia virus infection in non-intravenous drug using HIV seropositive men in Los Angeles.Aboulafia DM1991 Mar
1682022Expression of the immediate early gene c-fos in basal ganglia: induction by dopaminergic drugs.Robertson HA1991 Aug
1725703The molecular biology of addictive drugs.Mackler SA1991 Spring
1758988Epidemiological perspectives on children of alcoholics.Dinwiddie SH1991
1782144Hepatitis C in deceased drug addicts.Trubner K1991
1832466The dopamine D2 receptor locus as a modifying gene in neuropsychiatric disorders.Comings DE1991 Oct 2
1875992Synaptic regulation of the enkephalin gene and transcription factors in vivo: possible roles in drug abuse.Uhl GR1990
1903698Differential responsiveness of the pituitary-thyroid axis to thyrotropin-releasing hormone in mouse lines selected to differ in central nervous system sensitivity to ethanol.Erickson JD1991 Jun
1941526Diagnosis and differentiation of HTLV-I and HTLV-II infection by enzyme immunoassays using synthetic peptides.Viscidi RP1991
1975640Human dopamine D1 receptor encoded by an intronless gene on chromosome 5.Sunahara RK1990 Sep 6
2063922Clinical and genetic relationships between autism-pervasive developmental disorder and Tourette syndrome: a study of 19 cases.Comings DE1991 May 1
2065120Use of recombinant inbred strains to assess vulnerability to drug abuse at the genetic level.Phillips TJ1991
2118661Amphetamine and cocaine induce drug-specific activation of the c-fos gene in striosome-matrix compartments and limbic subdivisions of the striatum.Graybiel AM1990 Sep
2365666A controlled family history study of Tourette's syndrome, II: Alcoholism, drug abuse, and obesity.Comings DE1990 Jul
2596529Hypothesis: homozygosity in Tourette syndrome.Comings DE1989 Nov
2840804HIV receptor in brain and deduced peptides that block viral infectivity.Pert CB1988
2974511Cloning and expression of a rat D2 dopamine receptor cDNA.Bunzow JR1988 Dec 22-29
3144275Morphine activation of c-fos expression in rat brain.Chang SL1988 Dec 15
3163359Prognostic significance of adenosine deaminase determinations in subjects with the lymphoadenopathy syndrome.Casoli C1988 Apr
3167377The current age of youthful melancholia. Evidence for increase in depression among adolescents and young adults.Klerman GL1988 Jan
3417233Delta infection in asymptomatic carriers of hepatitis B surface antigen: low prevalence of delta activity and effective suppression of hepatitis B virus replication.Chen PJ1988 Sep-Oct
3475243[Acquired immunologic deficiency syndrome (AIDS). I. Biologic principles]Negele J1987 Jun
6455283Genetic screening of compounds used in drug abuse treatment. II. Methadone.Brusick D1981
7494469Programmed cell death in bacteria: proteic plasmid stabilization systems.Jensen RB1995 Jul
7494470Comparison of ccd of F, parDE of RP4, and parD of R1 using a novel conditional replication control system of plasmid R1.Jensen RB1995 Jul
7498314Transgenic superoxide dismutase mice differ in opioid-induced analgesia.Elmer GI1995 Sep 5
7506420Cellular adaptation to opiates alters ion-channel mRNA levels.Mackler SA1994 Jan 4
7550364Dopamine D2 receptor gene variants: association and linkage studies in impulsive-addictive-compulsive behaviour.Blum K1995 Jun
7573171DRD4 dopamine receptor genotype and CSF monoamine metabolites in Finnish alcoholics and controls.Adamson MD1995 Jun 19
7598467Hepatitis C: an overview.Bhandari BN1995
7647164Dopamine D2 receptor gene (DRD2) haplotypes and the defense style questionnaire in substance abuse, Tourette syndrome, and controls.Comings DE1995 Jun 1
7647833Tourette syndrome: a hereditary neuropsychiatric spectrum disorder.Comings DE1994 Dec
7681236Substance abuse vulnerability and D2 receptor genes.Uhl G1993 Mar
7694454Expression of the beta 1 chain (CD29) of integrins and CD45 in alcoholic liver disease. The VA Cooperative Study Group No. 275.Chedid A1993 Nov
7724703Chromosomal mapping of loci influencing sensitivity to cocaine-induced seizures in BXD recombinant inbred strains of mice.Miner LL1995 Jan
7752808Chromosomal localization of opioid peptide and receptor genes in the mouse.Giros B1995
7755894NMDA and D1 receptors mediate induction of c-fos and junB genes in striatum following morphine administration: implications for studies of memory.Sharp FR1995 Jan 23
7756606Decrease in CRE binding activity by chronic morphine administration in mouse brain.Ikemoto M1995 Jan 26
7774940Mapping of the taurine transporter gene to mouse chromosome 6 and to the short arm of human chromosome 3.Patel A1995 Jan 1
7774949Assignment of the creatine transporter gene (SLC6A8) to human chromosome Xq28 telomeric to G6PD.Gregor P1995 Jan 1
7802105Exclusion of close linkage of the dopamine transporter gene with schizophrenia spectrum disorders.Persico AM1995 Jan
7859110Molecular and cellular mechanisms of opiate action: studies in the rat locus coeruleus.Nestler EJ1994
7859833Molecular subtypes of env sequences around V3 region of human immunodeficiency virus type 1 in Taiwan.Chang KS1994 Jun
7881434Dinucleotide repeat polymorphism in the human taurine transporter gene (TAUT).Gregor P1994 Dec
7891851The dopamine transporter and dopamine D2 receptor messenger RNAs are differentially expressed in limbic- and motor-related subpopulations of human mesencephalic neurons.Hurd YL1994 Nov
7913352Association strategies in substance abuse.Uhl GR1994
7932176Genetic analysis of sensitization and tolerance to cocaine.Tolliver BK1994 Sep
7959416[Molecular diversity and properties of brain nicotinic acetylcholine receptor]Nakayama H1994 Sep
7959697Genetic and physical mapping of the GLUR5 glutamate receptor gene on human chromosome 21.Gregor P1994 Nov
7971989Regulation of expression of cAMP response element-binding protein in the locus coeruleus in vivo and in a locus coeruleus-like cell line in vitro.Widnell KL1994 Nov 8
8015373Reduction in dopamine transporter mRNA after cessation of repeated cocaine administration.Cerruti C1994 Mar
8026588cDNA cloning of an orphan opiate receptor gene family member and its splice variant.Wang JB1994 Jul 4
8033754The dopamine D2 receptor gene: a genetic risk factor in substance abuse.Comings DE1994 Feb
8057783'Choline/orphan V8-2-1/creatine transporter' mRNA is expressed in nervous, renal and gastrointestinal systems.Gonzalez AM1994 May
8071542Polymerase chain reaction analysis of hepatitis B virus DNA in formalin-fixed, paraffin-embedded liver biopsies from alcoholics using a simplified and standardized amplification protocol.von Weizsacker F1994 May
8075641Quantitative trait loci mapping of three loci controlling morphine preference using inbred mouse strains.Berrettini WH1994 May
8075641Quantitative trait loci mapping of three loci controlling morphine preference using inbred mouse strains.Berrettini WH1994 May
8078918Morphine induces c-fos and junB in striatum and nucleus accumbens via D1 and N-methyl-D-aspartate receptors.Liu J1994 Aug 30
8082550Genetic factors in substance abuse based on studies of Tourette syndrome and ADHD probands and relatives. I. Drug abuse.Comings DE1994 Mar
8082551Genetic factors in substance abuse based on studies of Tourette syndrome and ADHD probands and relatives. II. Alcohol abuse.Comings DE1994 Mar
8096458Dopamine D2 receptor gene Taq I 'A' locus map including 'A4' variant: relevance for alcoholism and drug abuse.Persico AM1993 Feb
8104042Comorbid psychopathy is not associated with increased D2 dopamine receptor TaqI A or B gene marker frequencies in incarcerated substance abusers.Smith SS1993 Jun 1-15
8216280Polymorphisms of the D4 dopamine receptor alleles in chronic alcoholism.George SR1993 Oct 15
8234282mu opiate receptor: cDNA cloning and expression.Wang JB1993 Nov 1
8255186Brain transcription factor expression: effects of acute and chronic amphetamine and injection stress.Persico AM1993 Oct
8260617Expression and novel subunit isoforms of glutamate receptor genes GluR5 and GluR6.Gregor P1993 Sep 30
8274284Drug addiction: a model for the molecular basis of neural plasticity.Nestler EJ1993 Dec
8309808Differential diagnosis and psychopharmacology of dual disorders.Decker KP1993 Dec
8328456Anticipation in bipolar affective disorder.McInnis MG1993 Aug
8341369Immediate early gene activation and long-term changes in neural function: a possible role in addiction?Robertson HA1993
8341370Regulation of neural gene expression in opiate and cocaine addiction.Nestler EJ1993
8381898Fos family member changes in nucleus caudalis neurons after primary afferent stimulation: enhancement of fos B and c-fos.Walther D1993 Jan
8385277Second messenger and protein phosphorylation mechanisms underlying opiate addiction: studies in the rat locus coeruleus.Guitart X1993 Jan
8385579Cellular responses to chronic treatment with drugs of abuse.Nestler EJ1993
8399824Dopamine transporter gene polymorphisms are not associated with polysubstance abuse.Persico AM1993 Aug 15
8411153Plasmid addiction genes of bacteriophage P1: doc, which causes cell death on curing of prophage, and phd, which prevents host death when prophage is retained.Lehnherr H1993 Oct 5
8413963Genomic imprinting and anticipation in idiopathic torsion dystonia.LaBuda MC1993 Oct
8445366Molecular characterization of two isolates of human T cell leukaemia virus type II from Italian drug abusers and comparison of genome structure with other isolates.Zella D1993 Mar
8464923Chromosomal localization of glutamate receptor genes: relationship to familial amyotrophic lateral sclerosis and other neurological disorders of mice and humans.Gregor P1993 Apr 1
8477052Ibogaine induces glial activation in parasagittal zones of the cerebellum.O'Hearn E1993 Mar
8488955DRD2 dopamine receptor genotype, linkage disequilibrium, and alcoholism in American Indians and other populations.Goldman D1993 Apr
8512534Quantitative trait loci (QTL) applications to substances of abuse: physical dependence studies with nitrous oxide and ethanol in BXD mice.Belknap JK1993 Mar
8582088Opioids and pain.Kanjhan R1995 Jun-Jul
8602733Transgenic mice: preproenkephalin and the mu opiate receptor.Donovan DM1996 Mar 22
8630246Addiction to cocaine and amphetamine.Hyman SE1996 May
8640219Identification of sex-specific quantitative trait loci controlling alcohol preference in C57BL/ 6 mice.Melo JA1996 Jun
8645779The D2 dopamine receptor gene, addiction, and personality: clinical correlates in cocaine abusers.Compton PA1996 Feb 15
8650219An Escherichia coli chromosomal "addiction module" regulated by guanosine [corrected] 3',5'-bispyrophosphate: a model for programmed bacterial cell death.Aizenman E1996 Jun 11
8661009The human serum paraoxonase/arylesterase gene (PON1) is one member of a multigene family.Primo-Parmo SL1996 May 1
8674469[The dopamine transporter: characterization and physiopathologic implications]Thibaut F1995 Nov-Dec
8698115Experimental liver fibrosis induced in rats receiving high doses of alcohol and alternating between regular and vitamin-depleted diets.Hirano H1996 Jul 15
8702525Autoregulation of the plasmid addiction operon of bacteriophage P1.Magnuson R1996 Aug 2
8747144Retained cocaine conditioned place preference in D1 receptor deficient mice.Miner LL1995 Nov 27
8750825Increased expression of synapsin I mRNA in defined areas of the rat central nervous system following chronic morphine treatment.Matus-Leibovitch N1995 Dec 28
8750881Prenatal morphine exposure differentially alters expression of opioid peptides in striatum of newborns.Tempel A1995 Nov
8784854Genetic factors in drug abuse and dependence.Comings DE1996
8794897Morphine down-regulates melanocortin-4 receptor expression in brain regions that mediate opiate addiction.Alvaro JD1996 Sep
8807661A study of the dopamine D2 receptor gene in pathological gambling.Comings DE1996 Jun
8825889Lack of association between alcohol-dependence and D3 dopamine receptor gene in three independent samples.Gorwood P1995 Dec 18
8825897Exclusion of close linkage between the synaptic vesicular monoamine transporter locus and schizophrenia spectrum disorders.Persico AM1995 Dec 18
8832655Effects of chronic nicotine treatment on the expression of phospholipase C isozymes and the alpha subunit of Gq/11 protein in the rat brain.Pandey SC1996 Jul 12
8837980Reduced dopaminergic function in alcoholics is related to severe dependence.Schmidt LG1996 Feb 1
8843485Individual and combined effects of ethanol and cocaine on intracellular signals and gene expression.Torres G1996 May
8845863The dopamine D2 receptor (DRD2) gene: a genetic risk factor in smoking.Comings DE1996 Feb
8859207Understanding drug addiction: implications for treatment.Leshner AI1996 Oct 15
8873216Increased prevalence of the Taq I A1 allele of the dopamine receptor gene (DRD2) in obesity with comorbid substance use disorder: a preliminary report.Blum K1996 Aug
8874837Dopamine D2 receptor (DRD2) gene and susceptibility to posttraumatic stress disorder: a study and replication.Comings DE1996 Sep 1
8889398Mating assortment and the liability to substance abuse.Vanyukov MM1996 Sep
8894071D2 dopamine receptor gene TaqI A1 and B1 restriction fragment length polymorphisms: enhanced frequencies in psychostimulant-preferring polysubstance abusers.Persico AM1996 Oct 15
8907305Allele-specific PCR for simultaneous amplification of both alleles of a deletion polymorphism in intron 6 of the human dopamine 2 receptor gene (DRD2).Finckh U1996
8943583Cocaine, dopamine and the endogenous opioid system.Kreek MJ1996
8947327Subtypes of alcohol-dependent men: a typology based on relative genetic and environmental loading.Johnson EO1996 Nov
8959019Novel transcription factors are induced by chronic cocaine treatment.Hope BT1996 Oct 31
8962158Cellular responses to psychomotor stimulant and neuroleptic drugs are abnormal in mice lacking the D1 dopamine receptor.Moratalla R1996 Dec 10
8974318Use of recombinant inbred strains for studying genetic determinants of responses to alcohol.Crabbe JC1994
8987796Quantitative trait loci affecting methamphetamine responses in BXD recombinant inbred mouse strains.Grisel JE1997 Jan 15
9023306Common quantitative trait loci for alcohol-related behaviors and central nervous system neurotensin measures: hypnotic and hypothermic effects.Erwin VG1997 Feb
9024952Allelic association of a dopamine transporter gene polymorphism in alcohol dependence with withdrawal seizures or delirium.Sander T1997 Feb 1
9044501Transcription factors: potential roles in drug-induced neuroplasticity.Persico AM1996 Oct-Dec
9067644Immunoregulatory effects of morphine on human lymphocytes.Nair MP1997 Mar
9075653Distribution of hepatitis C virus genotypes in German patients with chronic hepatitis C: correlation with clinical and virological parameters.Berg T1997 Mar
9095308The formation and measurement of DNA neuroadduction in alcoholism. Case report.Steinberg JJ1997 Mar
9106242Cannabinoid receptor gene (CNR1): association with i.v. drug use.Comings DE1997 Mar
9129716D2 dopamine receptor polymorphism and brain regional glucose metabolism.Noble EP1997 Apr 18
9133412Quantitative trait loci involved in genetic predisposition to acute alcohol withdrawal in mice.Buck KJ1997 May 15
9145787The mu-opioid receptor is necessary for [D-Pen2,D-Pen5]enkephalin-induced analgesia.Sora I1997 Apr 18
9152990Excess dopamine D4 receptor (D4DR) exon III seven repeat allele in opioid-dependent subjects.Kotler M1997 May
9197282Nicotine regulates mRNA level of tyrosine hydroxylase gene but not that of nicotinic acetylcholine receptor genes in PC12 cells.Ishiguro H1997 May 30
9221795rGbeta1: a psychostimulant-regulated gene essential for establishing cocaine sensitization.Wang XB1997 Aug 1
9259381High-activity catechol-O-methyltransferase allele is more prevalent in polysubstance abusers.Vandenbergh DJ1997 Jul 25
9294222FosB mutant mice: loss of chronic cocaine induction of Fos-related proteins and heightened sensitivity to cocaine's psychomotor and rewarding effects.Hiroi N1997 Sep 16
9326303Amino-terminal analysis of tryptophan hydroxylase: protein kinase phosphorylation occurs at serine-58.Kumer SC1997 Oct
9328073Dopaminergic genes and substance abuse.Uhl GR1998
9371903Gene locus FPD1 of the dystonic Mount-Reback type of autosomal-dominant paroxysmal choreoathetosis.Hofele K1997 Nov
9380041The dopamine transporter: a crucial component regulating dopamine transmission.Jaber M1997 Sep
9384550Molecular mechanisms of opiate and cocaine addiction.Nestler EJ1997 Oct
9387858Murine vesicular monoamine transporter 2: molecular cloning and genomic structure.Takahashi N1997 Oct 3
9394128Effects of prenatal ethanol exposure on phospholipase C-beta 1 and phospholipase A2 in hippocampus and medial frontal cortex of adult rat offspring.Allan AM1997 Nov
9398650Intronic sequences are involved in neural targeting of human dopamine transporter gene expression.Kouzmenko AP1997 Nov 26
9399693Genotypic selection provides experimental confirmation for an alcohol consumption quantitative trait locus in mouse.McClearn GE1997 Oct-Nov
9426133The poison-antidote stability system of the broad-host-range Thiobacillus ferrooxidans plasmid pTF-FC2.Smith AS1997 Dec
9427251Knockout of the vesicular monoamine transporter 2 gene results in neonatal death and supersensitivity to cocaine and amphetamine.Wang YM1997 Dec
9473720Subtracted differential display: genes with amphetamine-altered expression patterns include calcineurin.Wang XB1998 Jan
9489734Chronic ethanol treatment decreases [3H]epibatidine and [3H]nicotine binding and differentially regulates mRNA levels of nicotinic acetylcholine receptor subunits expressed in M10 and SH-SY5Y neuroblastoma cells.Gorbounova O1998 Mar
9491813Correlation of length of VNTR alleles at the X-linked MAOA gene and phenotypic effect in Tourette syndrome and drug abuse.Gade R1998 Jan
9498485Case-control study of the D2 dopamine receptor gene and smoking status in lung cancer patients.Spitz MR1998 Mar 4
9500675Genetic analysis of drug addiction: the role of cAMP response element binding protein.Blendy JA1998 Feb
9548265Hepatitis C virus genotypes: epidemiological and clinical associations. Benelux Study Group on Treatment of Chronic Hepatitis C.Kleter B1998 Feb
9560260The CCR5 receptor acts as an alloantigen in CCR5Delta32 homozygous individuals: identification of chemokineand HIV-1-blocking human antibodies.Ditzel HJ1998 Apr 28
9583233An association between a microsatellite polymorphism at the DRD5 gene and the liability to substance abuse: pilot study.Vanyukov MM1998 Mar
9600964Abolition of morphine-immunosuppression in mice lacking the mu-opioid receptor gene.Gaveriaux-Ruff C1998 May 26
9603521Increased vulnerability to cocaine in mice lacking the serotonin-1B receptor.Rocha BA1998 May 14
9603606Genome-wide search for genes affecting the risk for alcohol dependence.Reich T1998 May 8
9603607Evidence for genetic linkage to alcohol dependence on chromosomes 4 and 11 from an autosome-wide scan in an American Indian population.Long JC1998 May 8
9639280Differential regulation of the cloned kappa and mu opioid receptors.Tallent M1998 Aug
9645967Chronic administration of cannabinoids regulates proenkephalin mRNA levels in selected regions of the rat brain.Manzanares J1998 Mar 30
9655868Provisional mapping of quantitative trait loci for chronic ethanol withdrawal severity in BXD recombinant inbred mice.Crabbe JC1998 Jul
9660170The human mu opioid receptor gene: 5' regulatory and intronic sequences.Wendel B1998 Jun
9668659Cocaine and the AP-1 transcription factor complex.Hope BT1998 May 30
9668662Unraveling dopamine D3 receptor function in response to psychostimulants using a genetic approach.Xu M1998 May 30
9675304Effect of nicotine use and withdrawal on brain preproenkephalin A mRNA.Houdi AA1998 Jul 20
9677290The entericidin locus of Escherichia coli and its implications for programmed bacterial cell death.Bishop RE1998 Jul 24
9686001[Dopamine control of neuroendocrine functions. New findings based on the study of transgenic animals]Jaber M1997
9689128Single-nucleotide polymorphism in the human mu opioid receptor gene alters beta-endorphin binding and activity: possible implications for opiate addiction.Bond C1998 Aug 4
9691193Dopamine receptors and dopamine transporter in brain function and addictive behaviors: insights from targeted mouse mutants.Drago J1998
9691338[Rhabdomyolysis in carnitine palmitoyltransferase II deficiency: developments in pathophysiology, diagnosis and therapy]Imoberdorf R1998 Jun 20
9693390Genetically driven variation in serotonin uptake: is there a link to affective spectrum, neurodevelopmental, and neurodegenerative disorders?Lesch KP1998 Aug 1
9698095Lack of evidence of kappa2-selective activation of G-proteins: kappa opioid receptor stimulation of [35S] GTPgammaS binding in guinea pig brain.Childers SR1998 Jul 1
9702742Homozygosity at the dopamine D3 receptor gene is associated with opiate dependence.Duaux E1998 Jul
9713903Case-control, haplotype relative risk and transmission disequilibrium analysis of a dopamine D2 receptor functional promoter polymorphism in schizophrenia.Li T1998 Jul 27
9716929Relapse to drug-seeking: neural and molecular mechanisms.Self DW1998 Jun-Jul
9726281Confirmation of quantitative trait loci for alcohol preference in mice.Tarantino LM1998 Aug
9754945No heroin or morphine 6beta-glucuronide analgesia in mu-opioid receptor knockout mice.Kitanaka N1998 Aug 14
9756038Ethanol-induced conditioned taste aversion in BXD recombinant inbred mice.Risinger FO1998 Sep
9765582Autoregulation of the pTF-FC2 proteic poison-antidote plasmid addiction system (pas) is essential for plasmid stabilization.Smith AS1998 Oct
9767878[Transmission modes of hepatitis C virus]Karmochkine M1998 May 16
9768834Neuroscience of addiction.Koob GF1998 Sep
9783838Transgenic mice in drug dependence research.Pich EM1998 Aug
9789813Neural substrate of nicotine addiction as defined by functional brain maps of gene expression.Pich EM1998 Jun-Aug
9813289Effects of long-term exposure to delta9-THC on expression of cannabinoid receptor (CB1) mRNA in different rat brain regions.Zhuang S1998 Nov 20
9829946Corepression of the P1 addiction operon by Phd and Doc.Magnuson R1998 Dec
9852605Differential regulation of neurotrophin and trk receptor mRNAs in catecholaminergic nuclei during chronic opiate treatment and withdrawal.Numan S1998 Dec 15
9855288CB1 cannabinoid receptor antagonist-induced opiate withdrawal in morphine-dependent rats.Navarro M1998 Oct 26
9856954Regulation of cocaine reward by CREB.Carlezon WA Jr1998 Dec 18
98601165-HT3 receptor over-expression decreases ethanol self administration in transgenic mice.Engel SR1998 Nov
9860994rexB of bacteriophage lambda is an anti-cell death gene.Engelberg-Kulka H1998 Dec 22
9862779Dynorphin A1-13 causes elevation of serum levels of prolactin through an opioid receptor mechanism in humans: gender differences and implications for modulation of dopaminergic tone in the treatment of addictions.Kreek MJ1999 Jan
9866829[Structure and function of neural plasticity-related gene products]Yamagata K1998 Aug
9880575Identification of an acute ethanol response quantitative trait locus on mouse chromosome 2.Demarest K1999 Jan 15
9880655Alcohol preference in AXB/BXA recombinant inbred mice: gender differences and gender-specific quantitative trait loci.Gill K1998 Dec
9880656Genes on mouse chromosomes 2 and 9 determine variation in ethanol consumption.Phillips TJ1998 Dec
9880657A major influence of sex-specific loci on alcohol preference in C57Bl/6 and DBA/2 inbred mice.Peirce JL1998 Dec
9880659Genetics of ethanol-induced locomotor activation: detection of QTLs in a C57BL/6J x DBA/2J F2 intercross.Hitzemann R1998 Dec
9888857Unresponsiveness to cannabinoids and reduced addictive effects of opiates in CB1 receptor knockout mice.Ledent C1999 Jan 15
9925040A genetic association for cigarette smoking behavior.Sabol SZ1999 Jan
9929680Apolipoprotein E status is associated with odor identification deficits in nondemented older persons.Murphy C1998 Nov 30
9930873Hepatocyte growth factor gene therapy of liver cirrhosis in rats.Ueki T1999 Feb
10023512No association between D2 dopamine receptor (DRD2) alleles or haplotypes and cocaine dependence or severity of cocaine dependence in European- and African-Americans.Gelernter J1999 Feb 1
10025686A pharmacologic strategy for the treatment of nicotine addiction.Dewey SL1999 Jan
10068276Disorders in cell circuitry associated with multistage carcinogenesis: exploitable targets for cancer prevention and therapy.Weinstein IB1997 Dec
10082218[D-Ala2, D-Leu5]enkephalin blocks the methamphetamine-induced c-fos mRNA increase in mouse striatum.Hayashi T1999 Feb 5
10101608[Behavioral, cellular and molecular consequences of the dopamine transporter gene inactivation]Jaber M1998
10201639Chronic treatment with CP-55,940 regulates corticotropin releasing factor and proopiomelanocortin gene expression in the hypothalamus and pituitary gland of the rat.Corchero J1999
10208445Susceptibility genes for nicotine dependence: a genome scan and followup in an independent sample suggest that regions on chromosomes 2, 4, 10, 16, 17 and 18 merit further study.Straub RE1999 Mar
10213170Cocaethylene synthesis in Drosophila.Torres G1999 Mar 26
10218496Clusterin (SGP-2) gene expression is cell cycle dependent in normal human dermal fibroblasts.Bettuzzi S1999 Apr 9
10219981Repeated administration of delta9-tetrahydrocannabinol produces a differential time related responsiveness on proenkephalin, proopiomelanocortin and corticotropin releasing factor gene expression in the hypothalamus and pituitary gland of the rat.Corchero J1999 Mar
10230797The Drosophila dCREB2 gene affects the circadian clock.Belvin MP1999 Apr
10234039Enhancement of locomotor activity and conditioned reward to cocaine by brain-derived neurotrophic factor.Horger BA1999 May 15
10321497The proenkephalin gene (PENK) and opioid dependence.Comings DE1999 Apr 6
10366343Brain regions and drug addiction.Harlan RE1999 May 14
10379515Dopamine D4 receptor gene: novelty or nonsense?Paterson AD1999 Jul
10385682Inhibition of calcium/calmodulin-dependent protein kinase II in rat hippocampus attenuates morphine tolerance and dependence.Fan GH1999 Jul
10385932The role of cultural and social factors in the cause of addictive disorders.Westermeyer J1999 Jun
10385934Genetics of alcoholism and substance abuse.Enoch MA1999 Jun
10393893The mu opiate receptor as a candidate gene for pain: polymorphisms, variations in expression, nociception, and opiate responses.Uhl GR1999 Jul 6
10400893Interrupted expression of NAC-1 augments the behavioral responses to cocaine.Kalivas PW1999 Aug
10402503Studies of the 48 bp repeat polymorphism of the DRD4 gene in impulsive, compulsive, addictive behaviors: Tourette syndrome, ADHD, pathological gambling, and substance abuse.Comings DE1999 Aug 20
10407052Addiction-prone Lewis but not Fischer rats develop compulsive running that coincides with downregulation of nerve growth factor inducible-B and neuron-derived orphan receptor 1.Werme M1999 Jul 15
10411594The irreversible gamma-aminobutyric acid (GABA) transaminase inhibitor gamma-vinyl-GABA blocks cocaine self-administration in rats.Kushner SA1999 Aug
10413421Tobacco smoke carcinogens and lung cancer.Hecht SS1999 Jul 21
10415667The role of dopamine, dynorphin, and CART systems in the ventral striatum and amygdala in cocaine abuse.Hurd YL1999 Jun 29
10427709Proteic toxin-antitoxin, bacterial plasmid addiction systems and their evolution with special reference to the pas system of pTF-FC2.Rawlings DE1999 Jul 15
10432116Selective inhibition of cocaine-seeking behaviour by a partial dopamine D3 receptor agonist.Pilla M1999 Jul 22
10441742Genomic organization and mapping of the human and mouse neuronal beta2-nicotinic acetylcholine receptor genes.Lueders KK1999 Sep
10443995Identification and confirmation of quantitative trait loci regulating alcohol consumption in congenic strains of mice.Whatley VJ1999 Jul
10443995Identification and confirmation of quantitative trait loci regulating alcohol consumption in congenic strains of mice.Whatley VJ1999 Jul
10448422Glutamate and antimitotic agents induce differentiation, p53 activation, and apoptosis in rodent neostriatal cell lines immortalized with the tsA58 allele of SV40 large T antigen.Conejero C1999 Jul
10453464Targeted mutagenesis of the murine opioid system.Hayward MD1999
10471073Genetic contribution to pathological gambling: possible association between a functional DNA polymorphism at the serotonin transporter gene (5-HTT) and affected men.Perez de Castro I1999 Jun
10483044No association between the serotonin transporter promoter region (5-HTTLPR) and the dopamine D3 receptor (BalI D3DR) polymorphisms and heroin addiction.Kotler M1999 Jul
10490698Human delta-opioid receptor gene and susceptibility to heroin and alcohol dependence.Franke P1999 Oct 15
10499584Expression of the transcription factor deltaFosB in the brain controls sensitivity to cocaine.Kelz MB1999 Sep 16
10501478Sexual dimorphism in the response to N-methyl-D-aspartate receptor antagonists and morphine on behavior and c-Fos induction in the rat brain.D'Souza DN1999
10511013Drugs of abuse and brain gene expression.Torres G1999 Sep-Oct
10512487Knock-out mouse models used to study neurobiological systems.Picciotto MR1999
10520752Isolation and structural and genetic analysis of the mouse enkephalin gene and its d(AC/TG)n repeats.v Agoston D1998
10521591Heterozygous VMAT2 knockout mice display prolonged QT intervals: possible contributions to sudden death.Itokawa K1999 Aug 25
10534122Morphine promotes apoptosis in Jurkat cells.Singhal PC1999 Oct
10544257Identification and characterisation of novel polymorphisms in the CYP2A locus: implications for nicotine metabolism.Oscarson M1999 Oct 29
10547685Addiction modules and programmed cell death and antideath in bacterial cultures.Engelberg-Kulka H1999
10559418Null mutation of c-fos causes exacerbation of methamphetamine-induced neurotoxicity.Deng X1999 Nov 15
10560019Genetic approaches to studying norepinephrine function: knockout of the mouse norepinephrine transporter gene.Wang YM1999 Nov 1
10570040Selective potentiation of L-type calcium channel currents by cocaine in cardiac myocytes.Premkumar LS1999 Dec
10581396Cocaine reward and MPTP toxicity: alteration by regional variant dopamine transporter overexpression.Donovan DM1999 Nov 10
10591541Quantitative-trait loci analysis of cocaine-related behaviours and neurochemistry.Jones BC1999 Oct
10597438Exploring the impact of extended phenotype in stratified samples.Kovac I1999
10630609Glial differences between naive withdrawal seizure-prone and -resistant mice.Buckman JF1999 Dec
10642835A selective group of dopaminergic neurons express Nurr1 in the adult mouse brain.Backman C1999 Dec 18
10646497An allelic variation in the human prodynorphin gene promoter alters stimulus-induced expression.Zimprich A2000 Feb
10665625Molecular neurobiology for practicing psychiatrists, part 4: transferring the message of chemical neurotransmission from presynaptic neurotransmitter to postsynaptic gene expression.Stahl SM1999 Dec
10734168Cocaine-induced seizure thresholds: quantitative trait loci detection and mapping in two populations derived from the C57BL/6 and DBA/2 mouse strains.Hain HS2000 Apr
10739167CYP2D6 ultrarapid metabolizer genotype as a potential modifier of smoking behaviour.Saarikoski ST2000 Feb
10759218Gene therapy for liver cirrhosis.Fujimoto J2000 Mar
10774721Addiction, dopamine, and the molecular mechanisms of memory.Berke JD2000 Mar
10776669Impaired protein synthesis induced by acute alcohol intoxication is associated with changes in eIF4E in muscle and eIF2B in liver.Lang CH2000 Mar
10783304Disorders in cell circuitry during multistage carcinogenesis: the role of homeostasis.Weinstein IB2000 May
10798408Role for GDNF in biochemical and behavioral adaptations to drugs of abuse.Messer CJ2000 Apr
10810237Delta opioid peptide[D- Ala(2),D-Leu(5)]enkephalin promotes cell survival.Su TP2000 May-Jun
10814832Prior experience of morphine application alters the c-fos response to MDMA ('ecstasy') and cocaine in the rat striatum.Erdtmann-Vourliotis M2000 Apr 14
10829052Cancer risk and low-penetrance susceptibility genes in gene-environment interactions.Shields PG2000 Jun
10835636Mice deficient for delta- and mu-opioid receptors exhibit opposing alterations of emotional responses.Filliol D2000 Jun
10871694Genotype effects on neurodegeneration and neuroadaptation in monoaminergic neurotransmitter systems.Heinz A2000 Nov-Dec
10873460The thermodynamic stability of the proteins of the ccd plasmid addiction system.Dao-Thi MH2000 Jun 23
10875614HTLV type I/II in British Columbia Amerindians: a seroprevalence study and sequence characterization of an HTLV type IIa isolate.Peters AA2000 Jun 10
10881035Morphine-associated environmental cues elicit conditioned gene expression.Schroeder BE2000 Aug
10881203Addiction and its reward process through polymorphisms of the D2 dopamine receptor gene: a review.Noble EP2000 Mar
10881204Reappraisal of the association between the DRD2 gene, alcoholism and addiction.Gorwood P2000 Mar
10881207Genetic vulnerability to drug abuse.Duaux E2000 Mar
10881212Dopamine D3 receptor agents as potential new medications for drug addiction.Le Foll B2000 Mar
10887175Morphine induces gene expression of CCR5 in human CEMx174 lymphocytes.Miyagi T2000 Oct 6
10889531Human dopamine transporter gene: coding region conservation among normal, Tourette's disorder, alcohol dependence and attention-deficit hyperactivity disorder populations.Vandenbergh DJ2000 May
10900239Increased mesolimbic GABA concentration blocks heroin self-administration in the rat.Xi ZX2000 Aug
10911931Methadone-related opioid agonist pharmacotherapy for heroin addiction. History, recent molecular and neurochemical research and future in mainstream medicine.Kreek MJ2000
10921509Morphine stimulates mesangial cell TNF-alpha and nitrite production.Kapasi AA2000 Oct
10924661Levels of mRNAs encoding synaptic vesicle and synaptic plasma membrane proteins in the temporal cortex of elderly schizophrenic patients.Sokolov BP2000 Aug 1
10940942Localization of nicotinic receptor subunit mRNAs in monkey brain by in situ hybridization.Quik M2000 Sep 11
10942030Genetic dissection of nicotine-related behaviour: a review of animal studies.Mohammed AH2000 Aug
10942031Neuronal nicotinic acetylcholine receptors: from the gene to the disease.Weiland S2000 Aug
10952301DNA sequence of both chromosomes of the cholera pathogen Vibrio cholerae.Heidelberg JF2000 Aug 3
10958083Alcohol-induced locomotor activation in C57BL/6J, A/J, and AXB/BXA recombinant inbred mice: strain distribution patterns and quantitative trait loci analysis.Gill K2000 Jul
10984639Inhibition of the amygdala and hippocampal calcium/calmodulin-dependent protein kinase II attenuates the dependence and relapse to morphine differently in rats.Lu L2000 Sep 22
10994648Association of the neutral endopeptidase (MME) gene with anxiety.Comings DE2000 Jun
10998122Suppression of c-fos induction in the nucleus accumbens prevents acquisition but not expression of morphine-conditioned place preference.Tolliver BK2000 Sep
11003198Mapping of quantitative trait loci for hypnotic sensitivity to ethanol in crosses derived from the C57BL/6 and DBA/2 mouse strains.Radcliffe RA2000 Sep
11044752[(3)H]Nicotine binding in peripheral blood cells of smokers is correlated with the number of cigarettes smoked per day.Benhammou K2000 Oct
11054765The D(2) dopamine receptor A(1) allele and opioid dependence: association with heroin use and response to methadone treatment.Lawford BR2000 Oct 9
11054767Detection of single nucleotide polymorphisms of the human mu opioid receptor gene by hybridization or single nucleotide extension on custom oligonucleotide gelpad microchips: potential in studies of addiction.LaForge KS2000 Oct 9
11054768Association analysis of polymorphisms in the DRD4 gene and heroin abuse in Chinese subjects.Li T2000 Oct 9
11054773Antisociality, substance dependence, and the DRD5 gene: a preliminary study.Vanyukov MM2000 Oct 9
11054777Long forms of the dopamine receptor (DRD4) gene VNTR are more prevalent in substance abusers: no interaction with functional alleles of the catechol-o-methyltransferase (COMT) gene.Vandenbergh DJ2000 Oct 9
11059531Child health in the new millennium.Gracey M2000 Oct
11062465Genes and addiction.Nestler EJ2000 Nov
11064180A cocaine analog, 2beta-propanoyl-3beta-(4-tolyl)-tropane (PTT), reduces tyrosine hydroxylase in the mesolimbic dopamine pathway.Freeman WM2000 Dec 22
11064487Neurobiology of addictive behaviors and its relationship to methadone maintenance.Stimmel B2000 Oct-Nov
11067846A single nucleotide polymorphic mutation in the human mu-opioid receptor severely impairs receptor signaling.Befort K2001 Feb 2
11071896The regulation of the Escherichia coli mazEF promoter involves an unusual alternating palindrome.Marianovsky I2001 Feb 23
11089973Distinct functions of the two isoforms of dopamine D2 receptors.Usiello A2000 Nov 9
11093800Expression profiling of neural cells reveals specific patterns of ethanol-responsive gene expression.Thibault C2000 Dec
11102476Involvement of the extracellular signal-regulated kinase cascade for cocaine-rewarding properties.Valjent E2000 Dec 1
11102488Long-term nicotine adaptation in Caenorhabditis elegans involves PKC-dependent changes in nicotinic receptor abundance.Waggoner LE2000 Dec 1
11105655Reward deficiency syndrome: genetic aspects of behavioral disorders.Comings DE2000
11107549[Contribution of genetics to the concept of risk status for alcohol dependence]Gorwood P2000
11109025Scanning of five chromosomes for alcohol consumption loci.Vadasz C2000 Aug
11113963Impulsivity, aggression, and serotonin: a molecular psychobiological perspective.Lesch KP2000
11126428Nutrition, HIV, and drug abuse: the molecular basis of a unique role for selenium.Taylor EW2000 Oct 1
11134674Opioid receptor and peptide gene polymorphisms: potential implications for addictions.LaForge KS2000 Dec 27
11134675Pharmacogenomics and addiction to opiates.Lichtermann D2000 Dec 27
11141048Gene expression in human alcoholism: microarray analysis of frontal cortex.Lewohl JM2000 Dec
11146119Regulation of EphB1 expression by dopamine signaling.Halladay AK2000 Dec 28
11153280[Biological mechanisms of individual predisposition to psychoactive drug abuse]Anokhina IP2000 Nov-Dec
11165373Generation of dynorphin knockout mice.Sharifi N2001 Jan 31
11166067Effect of genetic cross on the detection of quantitative trait loci and a novel approach to mapping QTLs.Hitzemann R2000 Dec
11169780Delta opioid peptide [D-Ala2, D-Leu5]enkephalin causes a near complete blockade of the neuronal damage caused by a single high dose of methamphetamine: examining the role of p53.Hayashi T2001 Mar 15
11177525Genetic factors in addiction: QTL mapping and candidate gene studies implicate GABAergic genes in alcohol and barbiturate withdrawal in mice.Buck KJ2001 Jan
11178868Cocaine-induced expression of the tetraspanin CD81 and its relation to hypothalamic function.Brenz Verca MS2001 Feb
11200183ITF mapping after drugs of abuse: pharmacological versus perceptional effects.Ryabinin AE2000
11200184Effect of opioids on Ca2+/cAMP responsive element binding protein.Bilecki W2000
11222603Programmed cell death in Escherichia coli: some antibiotics can trigger mazEF lethality.Sat B2001 Mar
11222694Macrophage tropism of human immunodeficiency virus type 1 facilitates in vivo escape from cytotoxic T-lymphocyte pressure.Schutten M2001 Mar
11224382Genetic differences in the operant rate-depressant effects of ethanol between four inbred mouse strains.Elmor GI1995 Dec
11236836Genetic determinants of alcohol addiction and metabolism: a survey in Italy.Pastorelli R2001 Feb
11239920GABAergic blockade of cocaine-associated cue-induced increases in nucleus accumbens dopamine.Gerasimov MR2001 Mar 2
11245701GABA(A) receptors containing (alpha)5 subunits in the CA1 and CA3 hippocampal fields regulate ethanol-motivated behaviors: an extended ethanol reward circuitry.June HL2001 Mar 15
11252991Molecular basis of long-term plasticity underlying addiction.Nestler EJ2001 Feb
11261392A genetic association with the development of alcohol and other substance use behavior in Asian Americans.Wall TL2001 Feb
11268215Effects of chronic exposure to cocaine are regulated by the neuronal protein Cdk5.Bibb JA2001 Mar 15
11276410The genetics of alcoholism and alcohol abuse.Enoch MA2001 Apr
11292005Ethanol consumption and reward are decreased in mu-opiate receptor knockout mice.Hall FS2001 Feb
11295319Genes in drug abuse.Kuhar MJ2001 May 1
11299316Chronic cocaine-mediated changes in non-human primate nucleus accumbens gene expression.Freeman WM2001 Apr
11320258Molecular mechanisms of cocaine reward: combined dopamine and serotonin transporter knockouts eliminate cocaine place preference.Sora I2001 Apr 24
11324944The DRD4 gene and the spiritual transcendence scale of the character temperament index.Comings DE2000 Dec
11331423Effects of protracted nicotine exposure and withdrawal on the expression and phosphorylation of the CREB gene transcription factor in rat brain.Pandey SC2001 May
11333982BDNF controls dopamine D3 receptor expression and triggers behavioural sensitization.Guillin O2001 May 3
11337941Sensitivity of AXB/BXA recombinant inbred lines of mice to the locomotor activating effects of cocaine: a quantitative trait loci analysis.Boyle AE2001 Apr
11341850New directions in the genetic mechanisms underlying nicotine addiction.Munafo M2001 Apr
11341859The cannabinoid receptor gene (CNR1) is not affected in German i.v. drug users.Heller D2001 Apr
11344137Isolation of a new broad-host-range IncQ-like plasmid, pTC-F14, from the acidophilic bacterium Acidithiobacillus caldus and analysis of the plasmid replicon.Gardner MN2001 Jun
11347517[Genetics of addictive disorders]Rothhammer F2000 Nov
11353446An association study of DRD5 with smoking initiation and progression to nicotine dependence.Sullivan PF2001 Apr 8
11374326Dissecting the role of the serotonin system in neuropsychiatric disorders using knockout mice.Gingrich JA2001 Apr
11382384Cellular mRNA expression of the transcription factor NGFI-B suggests a gene regulatory role in striatal opiate-peptide neurons.Backman C2001 Jun 8
11391055Ethanol and gene expression in brain.Matsumoto I2001 May
11397804Depolarization strongly induces human cytomegalovirus major immediate-early promoter/enhancer activity in neurons.Wheeler DG2001 Aug 24
11406298Methamphetamine increases expression of the apoptotic c-myc and L-myc genes in the mouse brain.Thiriet N2001 Jun 20
11410714No association between the dopamine d2 receptor taqi a1 allele and earlier age of onset of alcohol dependence according to different specified criteria.Anghelescu I2001 Jun
11413684[Analysis of HIV-1 seropositive individual infected with different subtypes]Feng T2001 Mar
11414794Epileptogenesis and enhanced prepulse inhibition in GABA(B1)-deficient mice.Prosser HM2001 Jun
11420618Quantitative trait loci influencing morphine antinociception in four mapping populations.Bergeson SE2001 Jul
11424981Nonreplication of association between mu-opioid-receptor gene (OPRM1) A118G polymorphism and substance dependence.Franke P2001 Jan 8
11462745Attention deficit/hyperactivity disorder and substance abuse. Diagnostic and therapeutic considerations.Sullivan MA2001 Jun
11463816Mice with very low expression of the vesicular monoamine transporter 2 gene survive into adulthood: potential mouse model for parkinsonism.Mooslehner KA2001 Aug
11475799[Fom orphan receptor to novel neuropeptide: an example of reverse pharmacology]Meunier JC2001 May-Jun
11476594Time course study of GFRalpha-1 expression in an animal model of stroke.Sarabi A2001 Aug
11493327Liver steatosis in chronic hepatitis C: a morphological sign suggesting infection with HCV genotype 3.Rubbia-Brandt L2001 Aug
11494405Maturational increases in c-fos expression in the ascending dopamine systems.Andersen SL2001 Sep 15
11506703Transcriptional regulation of the human mu opioid receptor (hMOR) gene: evidence of positive and negative cis-acting elements in the proximal promoter and presence of a distal promoter.Xu Y2001 Jul
11506765Neuronal nicotinic receptors: from structure to function.Leonard S2001 Aug
11516821A common profile of prefrontal cortical activation following exposure to nicotine- or chocolate-associated contextual cues.Schroeder BE2001
11526201Gene expression following acute morphine administration.Loguinov AV2001 Aug 28
11528416Reinforcing and locomotor stimulant effects of cocaine are absent in mGluR5 null mutant mice.Chiamulera C2001 Sep
11529277Further characterization and high-resolution mapping of quantitative trait loci for ethanol-induced locomotor activity.Demarest K2001 Jan
11529590The oratory of addiction: a 30-year perspective on alcohol and drug misuse.Mackay IR2001 Aug
11535033Features of the replicon of plasmid pAM10.6 of Pseudomonas fluorescens.Peters M2001 Jul
115361865-HT(3)-receptor subunits A and B are co-expressed in neurons of the dorsal root ganglion.Morales M2001 Sep 17
11549749Facilitation of affiliation and pair-bond formation by vasopressin receptor gene transfer into the ventral forebrain of a monogamous vole.Pitkow LJ2001 Sep 15
11553044The additive effect of neurotransmitter genes in pathological gambling.Comings DE2001 Aug
11572966DeltaFosB: a sustained molecular switch for addiction.Nestler EJ2001 Sep 25
11576761Application of cDNA microarrays to examine gene expression differences in schizophrenia.Vawter MP2001 Jul 15
11605942Activation of mu-opioid receptor induces expression of c-fos and junB via mitogen-activated protein kinase cascade.Shoda T2001 Oct
11665331An integrative approach for studying the etiology of alcoholism and other addictions.Jacob T2001 Apr
11681595Toward a molecular understanding of psychostimulant actions using genetically engineered dopamine receptor knockout mice as model systems.Zhang J2001
11683987A novel cyclin provides a link between dopamine and RNA processing.Nairn AC2001 Oct 25
11689227Angiotensin converting enzyme gene--a candidate gene for addiction to smoking?Hubacek JA2001 Nov
11695946Twin studies of psychiatric illness: an update.Kendler KS2001 Nov
11704927Polysubstance abuse-vulnerability genes: genome scans for association, using 1,004 subjects and 1,494 single-nucleotide polymorphisms.Uhl GR2001 Dec
11707775The replicability of QTLs for murine alcohol preference drinking behavior across eight independent studies.Belknap JK2001 Dec
11715524[Effect of nitric oxide synthase inhibitor on signal transduction pathway of opiate tolerance and dependence in NG108-15 cells expressing iNOS gene]Zang M1999 Oct
11717377Different requirements for cAMP response element binding protein in positive and negative reinforcing properties of drugs of abuse.Walters CL2001 Dec 1
11720739Molecular biology of lung cancer.Kaye FJ2001 Dec
11738252Cocaine-responsive gene expression changes in rat hippocampus.Freeman WM2001
11744066Allelic and somatic variations in the endogenous opioid system of humans.Mayer P2001 Sep
11762133The genetics of addiction: alcohol-dependence and D3 dopamine receptor gene.Gorwood P2001 Nov
11772933Long-lasting increase in voluntary ethanol consumption and transcriptional regulation in the rat brain after intermittent exposure to alcohol.Rimondini R2002 Jan
11781512Summary report of a symposium: genes and gene delivery for diseases of alcoholism.Crews FT2001 Dec
11794078Drug addiction: a general review of new concepts and future challenges.Qureshi NA2000 Jul
11796656Sexually dimorphic effects of morphine and MK-801: sex steroid-dependent and -independent mechanisms.D'Souza DN2002 Feb
11803524Schizophrenia and the cannabinoid receptor type 1 (CB1): association study using a single-base polymorphism in coding exon 1.Leroy S2001 Dec 8
11805251Myoclonus dystonia: possible association with obsessive-compulsive disorder and alcohol dependence.Saunders-Pullman R2002 Jan 22
11812771KEPI, a PKC-dependent protein phosphatase 1 inhibitor regulated by morphine.Liu QR2002 Apr 12
11829123The effect of clonidine on the naltrexone-induced withdrawal response in morphine-treated guinea-pigs.Jungnickel S2002 Jan
11847428Profile of genes showing increased expression following dopamine and methamphetamine exposure in an immortalized neuronal cell line.Cai NS2001
11847429Gene expression profile in early stage of retinoic acid-induced differentiation of human SH-SY5Y neuroblastoma cells.Truckenmiller ME2001
11858765Single dose of morphine influences plasma corticosterone and gene expression of main NMDA receptor subunit in the adrenal gland but not in the hippocampus.Pirnik Z2001 Dec
11870259Neurobiology of relapse to heroin and cocaine seeking: a review.Shalev U2002 Mar
11880531Deletion of CCK2 receptor in mice results in an upregulation of the endogenous opioid system.Pommier B2002 Mar 1
11891796Differential expression of the "C" and "T" alleles of the 5-HT2A receptor gene in the temporal cortex of normal individuals and schizophrenics.Polesskaya OO2002 Mar 15
11913780Genomic organization of the murine G protein beta subunit genes and related processed pseudogenes.Kitanaka J2001 Dec
11916533Identification of novel ethanol-sensitive genes by expression profiling.Rahman S2001 Nov-Dec
11919667Mapping murine loci for physical dependence on ethanol.Buck KJ2002 Apr
11920678D1 dopamine receptor: a putative neurochemical and behavioral link to cocaine action.Hummel M2002 Apr
11929687Changes in the prevalence of hepatitis C virus (HCV) genotype 4 in Calabria, Southern Italy.Matera G2002 Mar
11933204Sequence variations in the mu-opioid receptor gene (OPRM1) associated with human addiction to heroin.Shi J2002 Apr
11936871Functional characterization of the promoter region of the human mu opioid receptor (hMOR) gene: identification of activating and inhibitory regions.Xu Y2001
11943848NMDA receptor function is regulated by the inhibitory scaffolding protein, RACK1.Yaka R2002 Apr 16
11950104The DRD4 VNTR polymorphism moderates craving after alcohol consumption.Hutchison KE2002 Mar
11955461Reduction of cocaine place preference in mice lacking the protein phosphatase 1 inhibitors DARPP 32 or Inhibitor 1.Zachariou V2002 Apr 15
11961130Methamphetamine causes coordinate regulation of Src, Cas, Crk, and the Jun N-terminal kinase-Jun pathway.Jayanthi S2002 May
11965355Molecular genetic approaches to investigate individual variations in behavioral and neuroendocrine stress responses.Mormede P2002 Jul
11975862Gender differences in tobacco smoking: higher relative exposure to smoke than nicotine in women.Zeman MV2002 Mar
11978849Congenic mapping of alcohol and pentobarbital withdrawal liability loci to a <1 centimorgan interval of murine chromosome 4: identification of Mpdz as a candidate gene.Fehr C2002 May 1
11978985Assignment of the mouse Park2 (PARKIN), the homologue to a new human Parkinson candidate gene, to the telomeric region of mouse 17A3.2-3.3, by in situ hybridization.Tomac AC2001
11992566Potentially functional polymorphism in the promoter region of prodynorphin gene may be associated with protection against cocaine dependence or abuse.Chen AC2002 May 8
12015197Exploring the opioid system by gene knockout.Kieffer BL2002 Apr
12045468Mapping of quantitative trait loci underlying ethanol metabolism in BXD recombinant inbred mouse strains.Grisel JE2002 May
12060782A missense mutation in human fatty acid amide hydrolase associated with problem drug use.Sipe JC2002 Jun 11
12060798CaMKII regulates amphetamine-induced ERK1/2 phosphorylation in striatal neurons.Choe ES2002 Jun 12
12061863AF5, a CNS cell line immortalized with an N-terminal fragment of SV40 large T: growth, differentiation, genetic stability, and gene expression.Truckenmiller ME2002 Jun
12065639Patterns of gene expression are altered in the frontal and motor cortices of human alcoholics.Mayfield RD2002 May
12073170Reinstatement of cocaine seeking in 129X1/SvJ mice: effects of cocaine priming, cocaine cues and food deprivation.Highfield DA2002 Jun
12074902Role of corticotropin-releasing hormone in the amygdala and bed nucleus of the stria terminalis in the behavioral, pain modulatory, and endocrine consequences of opiate withdrawal.McNally GP2002
12082567Characterisation, mutation detection, and association analysis of alternative promoters and 5' UTRs of the human dopamine D3 receptor gene in schizophrenia.Anney RJ2002
12084940Cocaine sensitization and reward are under the influence of circadian genes and rhythm.Abarca C2002 Jun 25
12098689Cancer. Addiction to oncogenes--the Achilles heal of cancer.Weinstein IB2002 Jul 5
12099908Amphetamine and cocaine do not increase Narp expression in rat ventral tegmental area, nucleus accumbens or prefrontal cortex, but Narp may contribute to individual differences in responding to a novel environment.Lu W2002 Jun
12105080Identification of chronic cocaine-induced gene expression through dopamine d1 receptors by using cDNA microarrays.Zhang J2002 Jun
12105083Ibogaine signals addiction genes and methamphetamine alteration of long-term potentiation.Onaivi ES2002 Jun
12105094Neurochemical changes and neurotoxic effects of an acute treatment with sydnocarb, a novel psychostimulant: comparison with D-amphetamine.Bashkatova V2002 Jun
12109875Microarray technology and its application on nicotine research.Li MD2002 Jun
12117546Changes in rat frontal cortex gene expression following chronic cocaine.Freeman WM2002 Jul 15
12117573Opioid modulation of taste hedonics within the ventral striatum.Kelley AE2002 Jul
12123445Gene expression profiling of Escherichia coli growth transitions: an expanded stringent response model.Chang DE2002 Jul
12130678Ethanol induces gene expression via nuclear compartmentalization of receptor for activated C kinase 1.He DY2002 Aug
12142011Substance abuse vulnerability loci: converging genome scanning data.Uhl GR2002 Aug
12165570CREB activity in the nucleus accumbens shell controls gating of behavioral responses to emotional stimuli.Barrot M2002 Aug 20
12173460[VNTR polymorphisms of the serotonin transporter and dopamine transporter genes in male opiate addicts]Galeeva AR2002 Jul-Aug
12176933Voluntary ethanol consumption by mice: genome-wide analysis of quantitative trait loci and their interactions in a C57BL/6ByJ x 129P3/J F2 intercross.Bachmanov AA2002 Aug
12180136Isolation and sequencing of a putative promoter region of the murine G protein beta 1 subunit (GNB1) gene.Kitanaka J2002 Feb
12205029cDNA array analysis of gene expression profiles in the striata of wild-type and Cu/Zn superoxide dismutase transgenic mice treated with neurotoxic doses of amphetamine.Krasnova IN2002 Sep
12223564Extrasynaptic alpha 7-nicotinic acetylcholine receptor expression in developing neurons is regulated by inputs, targets, and activity.Brumwell CL2002 Sep 15
12298263Chromosomal defects in 34 male homosexuals, half of them with HIV antibodies.Castro-Volio I2002 Mar
12349868Levels of analysis in psychiatric research.Kopnisky KL2002 Summer
12358776Repeated cocaine administration alters the expression of genes in corticolimbic circuitry after a 3-week withdrawal: a DNA macroarray study.Toda S2002 Sep
12359497Opioid receptor genes inactivated in mice: the highlights.Gaveriaux-Ruff C2002 Apr-Jun
12363385Microarray analysis of gene expression in the prefrontal cortex in schizophrenia: a preliminary study.Vawter MP2002 Nov 1
12373739Gamma-vinyl GABA, an irreversible inhibitor of GABA transaminase, alters the acquisition and expression of cocaine-induced sensitization in male rats.Gardner EL2002 Dec 15
12379259Withdrawal duration differentially affects c-fos expression in the medial prefrontal cortex and discrete subregions of the nucleus accumbens in cocaine-sensitized rats.Todtenkopf MS2002
12379882Applying genetic approaches to the treatment of nicotine dependence.Lerman C2002 Oct 21
12383778Experimental genetic approaches to addiction.Laakso A2002 Oct 10
12391261Mice with partial deficiency of c-Jun show attenuation of methamphetamine-induced neuronal apoptosis.Deng X2002 Nov
12394409Behavioral pharmacologists: don't just say "no" to knockout mice. Commentary on Stephens et al. 'Studying the neurobiology of stimulant and alcohol abuse and dependence in genetically manipulated mice'.Caine SB2002 Sep
12397092Active heroin administration induces specific genomic responses in the nucleus accumbens shell.Jacobs EH2002 Dec
12405989Characterization of the mouse adenylyl cyclase type VIII gene promoter: regulation by cAMP and CREB.Chao JR2002 Oct
12429408Locomotor sensitization to cocaine is associated with increased Fos expression in the accumbens, but not in the caudate.Crombag HS2002 Nov 15
12435434Hallucinogens and Drosophila: linking serotonin receptor activation to behavior.Nichols CD2002
12462416Repeated cocaine self-administration causes multiple changes in rat frontal cortex gene expression.Freeman WM2002 Oct
12464108Regulators of G protein signaling (RGS proteins): novel central nervous system drug targets.Neubig RR2002 Dec
12480179Kainate treatment alters TGF-beta3 gene expression in the rat hippocampus.Kim HC2002 Dec
12498903Interactions of the narcotic l-alpha-acetylmethadol with human cardiac K+ channels.Kang J2003 Jan 1
12500113Alcohol potentiates HIV-1 infection of human blood mononuclear phagocytes.Wang X2002 Dec
12503197Cancer genome targets: RAF-ing up tumor cells to overcome oncogene addiction.Workman P2002 Dec
12504868Methamphetamine potentiates HIV-1 Tat protein-mediated activation of redox-sensitive pathways in discrete regions of the brain.Flora G2003 Jan
12505704Gene expression profiling: methodological challenges, results, and prospects for addiction research.Pollock JD2002 Dec 31
12506708Generating gene knockout mice for studying mechanisms underlying drug addiction.Zhang J2003
12511956Extinction-induced upregulation in AMPA receptors reduces cocaine-seeking behaviour.Sutton MA2003 Jan 2
12520757Induction of GADD45 and GADD153 in neuroblastoma cells by dopamine-induced toxicity.Stokes AH2002 Dec
12523490Effect of cocaine and amphetamine on biosynthesis of proenkephalin and prodynorphin in some regions of the rat limbic system.Turchan J2002 Jul-Aug
12527475Lack of self-administration and behavioural sensitisation to morphine, but not cocaine, in mice lacking NK1 receptors.Ripley TL2002 Dec
12533537Recognition of the intrinsically flexible addiction antidote MazE by a dromedary single domain antibody fragment. Structure, thermodynamics of binding, stability, and influence on interactions with DNA.Lah J2003 Apr 18
12537867Netherlands Twin Register: a focus on longitudinal research.Boomsma DI2002 Oct
12563176Monoamine oxidase polymorphisms and smoking behaviour in Japanese.Ito H2003 Feb
12607907Factors involved in hepatic glutathione depletion induced by acute ethanol administration.Choi DW2000 Aug 11
12618374Comparative analysis of superintegrons: engineering extensive genetic diversity in the Vibrionaceae.Rowe-Magnus DA2003 Mar
12627475Family-based and case-control association studies of catechol-O-methyltransferase in attention deficit hyperactivity disorder suggest genetic sexual dimorphism.Qian Q2003 Apr 1
12629581Transcriptional profiling in the human prefrontal cortex: evidence for two activational states associated with cocaine abuse.Lehrmann E2003
12632192Effects of extracellular sodium on mu-opioid receptors coupled to potassium channels coexpressed in Xenopus oocytes.Oz M2003 Mar
12634255Murine retrovirus infection and the effect of chronic alcohol consumption: proteomic analysis of cardiac protein expression.Weekes J2003 Mar-Apr
12635538Genetics of pathological gambling.Ibanez A2003 Spring
12638131Gene expression profile from the striatum of amphetamine-treated rats: a cDNA array and in situ hybridization histochemical study.Gonzalez-Nicolini V2002 Oct
12653981Topography of cocaine-induced gene regulation in the rat striatum: relationship to cortical inputs and role of behavioural context.Willuhn I2003 Mar
12654662Use of genetically engineered phage to deliver antimicrobial agents to bacteria: an alternative therapy for treatment of bacterial infections.Westwater C2003 Apr
12657697Regulation of extracellular signal-regulated kinase by cannabinoids in hippocampus.Derkinderen P2003 Mar 15
12657709Striatal cell type-specific overexpression of DeltaFosB enhances incentive for cocaine.Colby CR2003 Mar 15
12670709Microarray analysis of genes expressed in the frontal cortex of rats chronically treated with morphine and after naloxone precipitated withdrawal.Ammon S2003 Apr 10
12675157Involvement of glutamate neurotransmission in the development of excessive wheel running in Lewis rats.Schwendt M2003 Apr
12679976[Dominant form of Diamond-Blackfan anemia]Stimac M2002 Nov-Dec
12684739Sub-chronic low dose gamma-vinyl GABA (vigabatrin) inhibits cocaine-induced increases in nucleus accumbens dopamine.Schiffer WK2003 Jul
12687634Differential gene expression in the rat caudate putamen after "binge" cocaine administration: advantage of triplicate microarray analysis.Yuferov V2003 Jun 15
12697293Differential expression of the cell line-derived neurotrophic factor (GDNF) receptor GFRalpha1 in heterozygous Gfralpha1 null-mutant mice after stroke.Sarabi A2003 May 8
12699766Differential psychostimulant-induced activation of neural circuits in dopamine transporter knockout and wild type mice.Trinh JV2003
12706249Inducible, brain region-specific expression of a dominant negative mutant of c-Jun in transgenic mice decreases sensitivity to cocaine.Peakman MC2003 Apr 25
12709300Analysis of methamphetamine-induced changes in the expression of integrin family members in the cortex of wild-type and c-fos knockout mice.Betts ES2002 Nov
12709305Brain-derived neurotrophic factor controls dopamine D3 receptor expression: implications for neurodevelopmental psychiatric disorders.Sokoloff P2002 Nov
12716423Molecular profiling of midbrain dopamine regions in cocaine overdose victims.Tang WX2003 May
12718862Dopaminergic supersensitivity in G protein-coupled receptor kinase 6-deficient mice.Gainetdinov RR2003 Apr 24
12718874Crystal structure of the MazE/MazF complex: molecular bases of antidote-toxin recognition.Kamada K2003 Apr
12726730Mu-opioid modulation of HIV-1 coreceptor expression and HIV-1 replication.Steele AD2003 Apr 25
12726824Amphetamine withdrawal modulates FosB expression in mesolimbic dopaminergic target nuclei: effects of different schedules of administration.Murphy CA2003 Jun
12727136Voluntary wheel running modulates glutamate receptor subunit gene expression and stress hormone release in Lewis rats.Makatsori A2003 Jul
12740597Candidate genes for anorexia nervosa in the 1p33-36 linkage region: serotonin 1D and delta opioid receptor loci exhibit significant association to anorexia nervosa.Bergen AW2003 Apr
12757967A genome-wide search for quantitative trait loci influencing substance dependence vulnerability in adolescence.Stallings MC2003 Jun 5
12769605Mutational analysis of the serotonergic system: recent findings using knockout mice.Gingrich JA2002 Oct
12774298Differential regulation by stimulants of neocortical expression of mrt1, arc, and homer1a mRNA in the rats treated with repeated methamphetamine.Fujiyama K2003 Sep 1
12774316Transcription profiling reveals mitochondrial, ubiquitin and signaling systems abnormalities in postmortem brains from subjects with a history of alcohol abuse or dependence.Sokolov BP2003 Jun 15
12782179Sigma receptors: potential medications development target for anti-cocaine agents.Matsumoto RR2003 May 23
12783266Nicotinic acetylcholine receptors: from structure to brain function.Hogg RC2003
12784114Reduced behavioral effects of cocaine in heterozygous brain-derived neurotrophic factor (BDNF) knockout mice.Hall FS2003 Aug
12805310Evidence for enhanced neurobehavioral vulnerability to nicotine during periadolescence in rats.Adriani W2003 Jun 1
12805318The glucocorticoid receptor as a potential target to reduce cocaine abuse.Deroche-Gamonet V2003 Jun 1
12805995An interactive database of cocaine-responsive gene expression.Freeman WM2002 Mar 12
12807435Regulation of ania-6 splice variants by distinct signaling pathways in striatal neurons.Sgambato V2003 Jul
12810711Characterization of the interactions within the mazEF addiction module of Escherichia coli.Zhang J2003 Aug 22
12814373Decreased ethanol preference and wheel running in Nurr1-deficient mice.Werme M2003 Jun
12819933The opportunities and challenges of personalized genome-based molecular therapies for cancer: targets, technologies, and molecular chaperones.Workman P2003 Jul
12821175Fos but not Cart (cocaine and amphetamine regulated transcript) is overexpressed by several drugs of abuse: a comparative study using real-time quantitative polymerase chain reaction in rat brain.Marie-Claire C2003 Jul 17
12835613Association between blood carisoprodol:meprobamate concentration ratios and CYP2C19 genotype in carisoprodol-drugged drivers: decreased metabolic capacity in heterozygous CYP2C19*1/CYP2C19*2 subjects?Bramness JG2003 Jul
12842300Elevated locomotor activity without altered striatal dopamine contents in Nurr1 heterozygous mice after acute exposure to methamphetamine.Backman C2003 Jul 14
12865893The pineal gland is critical for circadian Period1 expression in the striatum and for circadian cocaine sensitization in mice.Uz T2003 Dec
12871086Understanding the molecular mechanism of sigma-1 receptors: towards a hypothesis that sigma-1 receptors are intracellular amplifiers for signal transduction.Su TP2003 Oct
12878908Deletion of the fyn-kinase gene alters behavioral sensitivity to ethanol.Boehm SL 2nd2003 Jul
12884968Congenic C57BL/6 mu opiate receptor (MOR) knockout mice: baseline and opiate effects.Hall FS2003 Apr
12885430Effects of chronic dizocilpine on acute pain and on mRNA expression of neuropeptides and the dopamine and glutamate receptors.Al-Amin HA2003 Aug 15
12887598Relationship of Nef-positive and GFAP-reactive astrocytes to drug use in early and late HIV infection.Anderson CE2003 Aug
12892653Neuroendocrine alterations in a high-dose, extended-access rat self-administration model of escalating cocaine use.Mantsch JR2003 Oct
12893462Quantitative trait locus gene mapping: a new method for locating alcohol response genes.Crabbe JC1996
12898579Association between human mu-opioid receptor gene polymorphism, pain tolerance, and opioid addiction.Compton P2003 Aug 15
12899737Glucuronidation enzymes, genes and psychiatry.De Leon J2003 Mar
12925894Chromosomal loci influencing chronic alcohol withdrawal severity.Bergeson SE2003 Jul
12930795Phospholipase Cgamma in distinct regions of the ventral tegmental area differentially modulates mood-related behaviors.Bolanos CA2003 Aug 20
12932847HIV-1 protein Tat potentiation of methamphetamine-induced decreases in evoked overflow of dopamine in the striatum of the rat.Cass WA2003 Sep 12
12942997The use of microarrays to characterize neuropsychiatric disorders: postmortem studies of substance abuse and schizophrenia.Lehrmann E2003 Aug
13130513Novel putative nonprotein-coding RNA gene from 11q14 displays decreased expression in brains of patients with schizophrenia.Polesskaya OO2003 Oct 1
13680073Effects of rapid tryptophan depletion on mood and urge to drink in patients with co-morbid major depression and alcohol dependence.Pierucci-Lagha A2004 Jan
14517176Importance of ERK activation in behavioral and biochemical effects induced by MDMA in mice.Salzmann J2003 Nov
14521994The mouse nac1 gene, encoding a cocaine-regulated Bric-a-brac Tramtrac Broad complex/Pox virus and Zinc finger protein, is regulated by AP1.Mackler SA2003
14522087Cloning and characterization of a full-length pronociceptin in zebrafish: evidence of the existence of two different nociceptin sequences in the same precursor.Gonzalez-Nunez V2003 Oct 1
14534355A region-specific increase in Galphaq and Galpha11 proteins in brains of rats during cocaine withdrawal.Carrasco GA2003 Dec
14566342Regulation of gene expression and cocaine reward by CREB and DeltaFosB.McClung CA2003 Nov
14574230Cellular adaptation to chronic ethanol results in altered compartmentalization and function of the scaffolding protein RACK1.Vagts AJ2003 Oct
14595021Essential role for RGS9 in opiate action.Zachariou V2003 Nov 11
14595124Stable expression of hrGFP by mouse embryonic stem cells: promoter activity in the undifferentiated state and during dopaminergic neural differentiation.Zeng X2003
14607079Neuroadaptive effects of active versus passive drug administration in addiction research.Jacobs EH2003 Nov
14607263Novel insights into M5 muscarinic acetylcholine receptor function by the use of gene targeting technology.Yamada M2003 Dec 5
14612146Regulation of dopamine transporter function and plasma membrane expression by dopamine, amphetamine, and cocaine.Kahlig KM2003 Oct 31
14622092Nicotine-induced neuroprotection against N-methyl-D-aspartic acid or beta-amyloid peptide occur through independent mechanisms distinguished by pro-inflammatory cytokines.Gahring LC2003 Dec
14622103Differential distribution of CREB in the mesolimbic dopamine reward pathway.Walters CL2003 Dec
14622123Dopamine D1 receptors mediate CREB phosphorylation via phosphorylation of the NMDA receptor at Ser897-NR1.Dudman JT2003 Nov
14622243Transplantation of glial cell line-derived neurotrophic factor-expressing cells into the striatum and nucleus accumbens attenuates acquisition of cocaine self-administration in rats.Green-Sadan T2003 Oct
14625023Up-regulation of murine double minute clone 2 (MDM2) gene expression in rat brain after morphine, heroin, and cocaine administrations.Jiang Y2003 Dec 11
14631649Comparative inter-strain sequence analysis of the putative regulatory region of murine psychostimulant-regulated gene GNB1 (G protein beta 1 subunit gene).Kitanaka N2003 Aug
14643564The A1 allele of the DRD2 gene (TaqI A polymorphisms) is associated with antisocial personality in a sample of alcohol-dependent patients.Ponce G2003 Nov
14643766Chronic morphine treatment and withdrawal induce up-regulation of c-Jun N-terminal kinase 3 gene expression in rat brain.Fan XL2003
14648680Cannabinoid CB1 receptor and serotonin 3 receptor subunit A (5-HT3A) are co-expressed in GABA neurons in the rat telencephalon.Morales M2004 Jan 6
14659823Short interfering RNAs (siRNAs) for reducing dopaminergic phenotypic markers.Backman C2003 Dec 30
14679582A genomic scan for habitual smoking in families of alcoholics: common and specific genetic factors in substance dependence.Bierut LJ2004 Jan 1
14698760Altered neurotensin mrna expression in mice lacking the dopamine transporter.Roubert C2004
14706429Functional polymorphisms in the sigma1 receptor gene associated with alcoholism.Miyatake R2004 Jan 1
14710532[Schizophrenia and drug abuse: genetic aspects]Poirier MF2003 Sep
14712399Modulation of simian immunodeficiency virus neuropathology by dopaminergic drugs.Czub S2004 Mar
14732864Stress-induced cigarette craving: effects of the DRD2 TaqI RFLP and SLC6A3 VNTR polymorphisms.Erblich J2004
14741421Association of drug abuse with inhibition of HIV-1 immune responses: studies with long-term of HIV-1 non-progressors.Nair MP2004 Feb
14741432Chronic morphine treatment differentiates T helper cells to Th2 effector cells by modulating transcription factors GATA 3 and T-bet.Roy S2004 Feb
14746512Molecular neurobiology of drug addiction.Chao J2004
14751274Up-regulation of gamma-aminobutyric acid transporter I mediates ethanol sensitivity in mice.Hu JH2004
14755456Haplotypes of the monoamine oxidase genes and the risk for substance use disorders.Vanyukov MM2004 Feb 15
14871405Protease inhibitors modulate apoptosis in mesangial cells derived from a mouse model of HIVAN.Mongia A2004 Mar
14969743micro-Opioid receptor knockout mice display reduced cocaine conditioned place preference but enhanced sensitization of cocaine-induced locomotion.Hall FS2004 Feb 5
14975171A genome-wide scan to identify loci for smoking rate in the Framingham Heart Study population.Li MD2003
14975172Mapping susceptibility loci for alcohol consumption using number of grams of alcohol consumed per day as a phenotype measure.Ma JZ2003
14975676Neurofilament proteins and cAMP pathway in brains of mu-, delta- or kappa-opioid receptor gene knock-out mice: effects of chronic morphine administration.Garcia-Sevilla JA2004 Mar
15002731Microarray analysis of mouse brain gene expression following acute ethanol treatment.Treadwell JA2004 Feb
15009677Gene expression profile of the nucleus accumbens of human cocaine abusers: evidence for dysregulation of myelin.Albertson DN2004 Mar
15019433Involvement of cholinergic neuronal systems in intravenous cocaine self-administration.Smith JE2004 Jan
15024022Interference of mRNA function by sequence-specific endoribonuclease PemK.Zhang J2004 May 14
15024690Variations in GABRA2, encoding the alpha 2 subunit of the GABA(A) receptor, are associated with alcohol dependence and with brain oscillations.Edenberg HJ2004 Apr
15024965Neuroimaging and mechanisms of drug abuse: interface of molecular imaging and molecular genetics.Ernst M2003 Nov
15026155Acupuncture attenuates repeated nicotine-induced behavioral sensitization and c-Fos expression in the nucleus accumbens and striatum of the rat.Chae Y2004 Mar 25
15028698Plasmid evolution and interaction between the plasmid addiction stability systems of two related broad-host-range IncQ-like plasmids.Deane SM2004 Apr
15034918Kinetics of beta-funaltrexamine binding to wild-type and mutant mu-opioid receptors expressed in Chinese hamster ovary cells.Spivak CE2004 May
15037869Substantial attributable risk related to a functional mu-opioid receptor gene polymorphism in association with heroin addiction in central Sweden.Bart G2004 Jun
15042644Diversity and origin of hepatitis B virus in Dutch blood donors.Koppelman MH2004 May
15072584Development of gene therapy to target pancreatic cancer.Yoshida T2004 Apr
15075460Role of the brain-gut axis in alcohol-related gastrointestinal diseases - What can we learn from new animal models?Siegmund S2003 Dec
15077008Nicotine dependence in a prospective population-based study of adolescents: the protective role of a functional tyrosine hydroxylase polymorphism.Anney RJ2004 Feb
15082182Reduction of withdrawal signs after chronic nicotine exposure of alpha-calcitonin gene-related peptide knock-out mice.Salmon AM2004 Apr 22
15086512Effect of the A118G polymorphism on binding affinity, potency and agonist-mediated endocytosis, desensitization, and resensitization of the human mu-opioid receptor.Beyer A2004 May
15090510Modular organization of the Phd repressor/antitoxin protein.Smith JA2004 May
15107718[Dependence on zolpidem: a report of two cases]Boulanger-Rostowsky L2004 Mar-Apr
15109829Nucleotide sequence of the cryptic plasmid pTT8 from Thermus thermophilus HB8 and isolation and characterization of its high-copy-number mutant.Takayama G2004 May
15126682Protein kinase C isozymes and addiction.Olive MF2004 Apr
15131342Functional genomic analysis in pain research using hybridization arrays.Walker SJ2004
15135221Opiate-like effects of sugar on gene expression in reward areas of the rat brain.Spangler R2004 May 19
15140009Identifying polymorphisms in the Rattus norvegicus D3 dopamine receptor gene and regulatory region.Smits BM2004 Jun
15146457Identification and characterization of ANKK1: a novel kinase gene closely linked to DRD2 on chromosome band 11q23.1.Neville MJ2004 Jun
15153607Properties of pluripotent human embryonic stem cells BG01 and BG02.Zeng X2004
15154117A common haplotype of the nicotine acetylcholine receptor alpha 4 subunit gene is associated with vulnerability to nicotine addiction in men.Feng Y2004 Jul
15157990Chronic nicotine and smoking treatment increases dopamine transporter mRNA expression in the rat midbrain.Li S2004 Jun 3
15159536Gene knockout of glycine transporter 1: characterization of the behavioral phenotype.Tsai G2004 Jun 1
15175423Short-term cocaine treatment causes neuroadaptive changes in Galphaq and Galpha11 proteins in rats undergoing withdrawal.Carrasco GA2004 Oct
15184239Association of specific haplotypes of D2 dopamine receptor gene with vulnerability to heroin dependence in 2 distinct populations.Xu K2004 Jun
15194118Mu opioid receptor: a gateway to drug addiction.Contet C2004 Jun
15196794Molecular mechanisms in dizocilpine-induced attenuation of development of morphine dependence: an association with cortical Ca2+/calmodulin-dependent signal cascade.Hamdy MM2004 Jul 9
15197345Gefitinib (iressa) in oncogene-addictive cancers and therapy for common cancers.Blagosklonny MV2004 May
15198681Long-term regulation of signalling components of adenylyl cyclase and mitogen-activated protein kinase in the pre-frontal cortex of human opiate addicts.Ferrer-Alcon M2004 Jul
15208631Mpdz is a quantitative trait gene for drug withdrawal seizures.Shirley RL2004 Jul
15211639Polymorphism of 5HT2A serotonin receptor gene is implicated in smoking addiction.do Prado-Lima PA2004 Jul 1
15211640Results of a genomewide linkage scan: support for chromosomes 9 and 11 loci increasing risk for cigarette smoking.Gelernter J2004 Jul 1
15217373Preferential vulnerability of astroglia and glial precursors to combined opioid and HIV-1 Tat exposure in vitro.Khurdayan VK2004 Jun
15225772Association between AIDS disease progression rates and the Fok-I polymorphism of the VDR gene in a cohort of HIV-1 seropositive patients.Nieto G2004 May
15231726M4 muscarinic receptors regulate the dynamics of cholinergic and dopaminergic neurotransmission: relevance to the pathophysiology and treatment of related CNS pathologies.Tzavara ET2004 Sep
15236863Decreased expression of NEFH and PCP4/PEP19 in the prefrontal cortex of alcoholics.Iwamoto K2004 Aug
15251884Adolescent development of forebrain stimulant responsiveness: insights from animal studies.Leslie FM2004 Jun
15254019Reduced cellular expression and activity of the P129T mutant of human fatty acid amide hydrolase: evidence for a link between defects in the endocannabinoid system and problem drug use.Chiang KP2004 Sep 15
15254092The rate of cocaine administration alters gene regulation and behavioral plasticity: implications for addiction.Samaha AN2004 Jul 14
15266655Repetitive exposures to nicotine induce a hyper-responsiveness via the cAMP/PKA/CREB signal pathway in Drosophila.Hou J2004 Aug
15270299[Association study of NcoI and TaqI A dopamine receptor D2 gene polymorphism in opium addicts]Gareeva AE2004
15274053Association analysis of the DRD4 and COMT genes in methamphetamine abuse.Li T2004 Aug 15
15282116Mouse striatal transcriptome analysis: effects of oral self-administration of alcohol.Saito M2004 Apr
15287893Activation of AP-1 and CRE-dependent gene expression via mu-opioid receptor.Bilecki W2004 Aug
15289816Human cannabinoid receptor 1: 5' exons, candidate regulatory regions, polymorphisms, haplotypes and association with polysubstance abuse.Zhang PW2004 Oct
15294147Homer proteins regulate sensitivity to cocaine.Szumlinski KK2004 Aug 5
15312160Gene expression profiling of individual cases reveals consistent transcriptional changes in alcoholic human brain.Liu J2004 Sep
15334604Proteomic analysis of phosphotyrosyl proteins in the rat brain: effect of butorphanol dependence.Kim SY2004 Sep 15
15334606Modulation of CREB expression and phosphorylation in the rat nucleus accumbens during nicotine exposure and withdrawal.Pluzarev O2004 Sep 15
15339882Genetic basis of tobacco smoking: strong association of a specific major histocompatibility complex haplotype on chromosome 6 with smoking behavior.Fust G2004 Oct
15353588Molecular basis for catecholaminergic neuron diversity.Grimm J2004 Sep 21
15379885Effects of morphine on gene expression in the rat amygdala.Rodriguez Parkitna JM2004 Oct
15381926Effects of dopamine D2 receptor (DRD2) and transporter (SLC6A3) polymorphisms on smoking cue-induced cigarette craving among African-American smokers.Erblich J2005 Apr
15386001Analgesia: morphine-pathway block in top1 poppies.Millgate AG2004 Sep 23
15388282Diurnal rhythms in cocaine sensitization and in Period1 levels are common across rodent species.Akhisaroglu M2004 Sep
15388296The effects of cocaine on the rate independent brain stimulation reward threshold in the mouse.Gill BM2004 Sep
15459944Association study between brain-derived neurotrophic factor gene polymorphisms and methamphetamine abusers in Japan.Itoh K2005 Jan 5
15462238Pleasure: from onthogenesis to addiction.Margaron H2004 Jul
15464029Dopamine receptors in C. elegans.Suo S2004 Oct 1
15464044Opioid abuse and brain gene expression.Przewlocki R2004 Oct 1
15464123Molecular mechanisms of drug addiction.Nestler EJ2004
15464129Genetic and genomic approaches to reward and addiction.Mohn AR2004
15464133Molecular genetic underpinnings of human substance abuse vulnerability: likely contributions to understanding addiction as a mnemonic process.Uhl GR2004
15464447Mutations and addiction to EGFR: the Achilles 'heal' of lung cancers?Gazdar AF2004 Oct
15466321Extinction training regulates neuroadaptive responses to withdrawal from chronic cocaine self-administration.Self DW2004 Sep-Oct
15466698Sigma-1 receptors at galactosylceramide-enriched lipid microdomains regulate oligodendrocyte differentiation.Hayashi T2004 Oct 12
15467399Neuroglycan C, a brain-specific part-time proteoglycan, with a particular multidomain structure.Oohira A2004
15469049Anti-opioid systems in morphine tolerance and addiction--locus-specific involvement of nociceptin and the NMDA receptor.Ueda H2004
15470197Extracellular receptor kinase and cAMP response element binding protein activation in the neonatal rat heart after perinatal cocaine exposure.Sun LS2004 Dec
15470592International Narcotics Research Conference-35th Meeting. Current developments in medicinal chemistry in the opioid field 17-24 July 2004, Kyoto, Japan.Kitchen I2004 Sep
15488239Tetracycline-inducible expression systems for the generation of transgenic animals: a comparison of various inducible systems carried in a single vector.Backman CM2004 Oct 30
15492764Dopamine receptor DRD2 genotype and smoking cessation outcome following treatment with bupropion SR.Swan GE2005
15496936Brief social defeat stress: long lasting effects on cocaine taking during a binge and zif268 mRNA expression in the amygdala and prefrontal cortex.Covington HE 3rd2005 Feb
15500908The gene transcription factor cyclic AMP-responsive element binding protein: role in positive and negative affective states of alcohol addiction.Pandey SC2004 Oct
15508023Confirmation of a major QTL influencing oral morphine intake in C57 and DBA mice using reciprocal congenic strains.Ferraro TN2005 Apr
15517021RNAi and HTS: exploring cancer by systematic loss-of-function.Willingham AT2004 Nov 1
15530653L-type Ca2+ channel blockers promote Ca2+ accumulation when dopamine receptors are activated in striatal neurons.Eaton ME2004 Nov 24
15541508The expanding role of PSD-95: a new link to addiction.Roche KW2004 Dec
15542694Molecular genetics of substance abuse vulnerability: remarkable recent convergence of genome scan results.Uhl GR2004 Oct
15542695The application of proteomics to the human alcoholic brain.Lewohl JM2004 Oct
15542696No association found between the type 1 sigma receptor gene polymorphisms and methamphetamine abuse in the Japanese population: a collaborative study by the Japanese Genetics Initiative for Drug Abuse.Inada T2004 Oct
15542697No association is found between the candidate genes of t-PA/plasminogen system and Japanese methamphetamine-related disorder: a collaborative study by the Japanese Genetics Initiative for Drug Abuse.Iwata N2004 Oct
15542705Changes in expression of the mouse homologues of KIAA genes after subchronic methamphetamine treatment.Yamamoto H2004 Oct
15542713Substituted amphetamines that produce long-term serotonin depletion in rat brain ("neurotoxicity") do not decrease serotonin transporter protein expression.Rothman RB2004 Oct
15542722Fos expression associated with the discriminative stimulus effects of methamphetamine in rats.Zeng N2004 Oct
15542732Gene polymorphisms of the mu opioid receptor in methamphetamine abusers.Ide S2004 Oct
15542739Locus-specific involvement of anti-opioid systems in morphine tolerance and dependence.Ueda H2004 Oct
15542751Influence of genetic variations of ethanol-metabolizing enzymes on phenotypes of alcohol-related disorders.Higuchi S2004 Oct
15545018Gene-environment interplay in alcoholism and other substance abuse disorders: expressions of heritability and factors influencing vulnerability.Palomo T2004
15545022Homer2 gene deletion in mice produces a phenotype similar to chronic cocaine treated rats.Kalivas PW2004
15547445Association study of brain-derived neurotrophic factor gene polymorphism and alcoholism.Matsushita S2004 Nov
15547783Neurosteroids and sigma1 receptors, biochemical and behavioral relevance.Maurice T2004 Nov
15548228A single high dose of cocaine induces behavioural sensitization and modifies mRNA encoding GluR1 and GAP-43 in rats.Grignaschi G2004 Nov
15548669RACK1 and brain-derived neurotrophic factor: a homeostatic pathway that regulates alcohol addiction.McGough NN2004 Nov 17
15550451Interactions between cannabinoid and opioid receptor systems in the mediation of ethanol effects.Manzanares J2005 Jan-Feb
15574356Quantification of HIV GAG RNA using real time reverse transcriptase PCR.Shapshak P2005 Jan 1
15574887Characterization of the novel Fusobacterium nucleatum plasmid pKH9 and evidence of an addiction system.Bachrach G2004 Dec
15581469[Alcohol dependence and polymorphisms of serotonin-related genes]Gorwood P2004 Dec
15582154DeltaFosB: a molecular switch for long-term adaptation in the brain.McClung CA2004 Dec 20
15582156Time-dependent changes in transcriptional profiles within five rat brain regions in response to nicotine treatment.Li MD2004 Dec 20
15582580Proteomic analysis of nicotine-associated protein expression in the striatum of repeated nicotine-treated rats.Yeom M2005 Jan 14
15585414Genetically engineered dopamine beta-hydroxylase gene promoters with better PHOX2-binding sites drive significantly enhanced transgene expression in a noradrenergic cell-specific manner.Hwang DY2005 Jan
15587964Gene-environment interaction in nicotine addiction: the need for a large-scale, collaborative effort.Swan GE2004
15607957Oncogene addiction: sometimes a temporary slavery.Jonkers J2004 Dec
15608558Redefinition of the human kappa opioid receptor gene (OPRK1) structure and association of haplotypes with opiate addiction.Yuferov V2004 Dec
15608559The human serotonin receptor 2B: coding region polymorphisms and association with vulnerability to illegal drug abuse.Lin Z2004 Dec
15610180In vivo gene delivery of urokinase-type plasminogen activator with regulatable lentivirus induces behavioural changes in chronic cocaine administration.Bahi A2004 Dec
15629761Truncated N-terminal mutants of SV40 large T antigen as minimal immortalizing agents for CNS cells.Freed WJ2005 Feb
15629948Characterization of the Phd repressor-antitoxin boundary.McKinley JE2005 Jan
15635702Pleiotropic effect of the TPH A779C polymorphism on nicotine dependence and personality.Reuter M2005 Apr 5
15640183Persistence of animal and human glycopeptide-resistant enterococci on two Norwegian poultry farms formerly exposed to avoparcin is associated with a widespread plasmid-mediated vanA element within a polyclonal enterococcus faecium population.Johnsen PJ2005 Jan
15642598Neuroadaptations to hyperdopaminergia in dopamine D3 receptor-deficient mice.Le Foll B2005 Jan 28
15654288Accumbal strychnine-sensitive glycine receptors: an access point for ethanol to the brain reward system.Molander A2005 Jan
15661365Proteomic analysis of phosphotyrosyl proteins in morphine-dependent rat brains.Kim SY2005 Jan 5
15661619Genetic disposition to addictive disorders--current knowledge and future perspectives.Mayer P2005 Feb
15661622Gene expression induced by drugs of abuse.Rhodes JS2005 Feb
15665076Increased activity of cyclin-dependent kinase 5 leads to attenuation of cocaine-mediated dopamine signaling.Takahashi S2005 Feb 1
15666084Protein kinase C regulation of GABAA receptors.Song M2005 Jan
15666411Human brain derived neurotrophic factor (BDNF) genes, splicing patterns, and assessments of associations with substance abuse and Parkinson's Disease.Liu QR2005 Apr 5
15670622Stroke and TGF-beta proteins: glial cell line-derived neurotrophic factor and bone morphogenetic protein.Harvey BK2005 Feb
15673448Repeated morphine treatment alters polysialylated neural cell adhesion molecule, glutamate decarboxylase-67 expression and cell proliferation in the adult rat hippocampus.Kahn L2005 Jan
15680202Ginsenosides attenuate methamphetamine-induced behavioral side effects in mice via activation of adenosine A2A receptors: possible involvements of the striatal reduction in AP-1 DNA binding activity and proenkephalin gene expression.Shin EJ2005 Mar 7
15680308Basal opioid receptor activity, neutral antagonists, and therapeutic opportunities.Sadee W2005 Feb 11
15691709Cocaine-induced expression changes of axon guidance molecules in the adult rat brain.Bahi A2005 Feb
15700285Amphetamine withdrawal produces region-specific and time-dependent changes in connexin36 expression in rat brain.McCracken CB2005 Apr
15703390A specific limbic circuit underlies opiate withdrawal memories.Frenois F2005 Feb 9
15704216Association between the DRD2 A1 allele and opium addiction in the Iranian population.Shahmoradgoli Najafabadi M2005 Apr 5
15705350Rapid delivery of nicotine promotes behavioral sensitization and alters its neurobiological impact.Samaha AN2005 Feb 15
15706614Effect of chronic morphine exposure on the synaptic plasma-membrane subproteome of rats: a quantitative protein profiling study based on isotope-coded affinity tags and liquid chromatography/mass spectrometry.Prokai L2005 Feb
15713712Effect of leptin replacement on brain structure in genetically leptin-deficient adults.Matochik JA2005 May
15714041CREB gene transcription factors: role in molecular mechanisms of alcohol and drug addiction.Pandey SC2005 Feb
15731118Joint analysis of the NACP-REP1 marker within the alpha synuclein gene concludes association with alcohol dependence.Bonsch D2005 Apr 1
15734726Pharmacogenetics and human molecular genetics of opiate and cocaine addictions and their treatments.Kreek MJ2005 Mar
15743936Percolation of the phd repressor-operator interface.Zhao X2005 Mar
15745951Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice.Kerns RT2005 Mar 2
15750634Bacterial death comes full circle: targeting plasmid replication in drug-resistant bacteria.DeNap JC2005 Mar 21
15753323Enhanced cocaine responsiveness and impaired motor coordination in metabotropic glutamate receptor subtype 2 knockout mice.Morishima Y2005 Mar 15
15759211Single- and multilocus allelic variants within the GABA(B) receptor subunit 2 (GABAB2) gene are significantly associated with nicotine dependence.Beuten J2005 May
15765533Phospholipase C gamma in distinct regions of the ventral tegmental area differentially regulates morphine-induced locomotor activity.Bolanos CA2005 Jun 1
15770241Repeated cocaine administration induces gene expression changes through the dopamine D1 receptors.Zhang D2005 Aug
15777776Morphine causes a delayed increase in glutamate receptor functioning in the nucleus accumbens core.Jacobs EH2005 Mar 21
15778854Kappa opioid receptor is expressed in the rat cerebellar cortex.Herraez-Baranda LA2005 May
15790597Ethnic- and gender-specific association of the nicotinic acetylcholine receptor alpha4 subunit gene (CHRNA4) with nicotine dependence.Li MD2005 May 1
15798361BG01V: a variant human embryonic stem cell line which exhibits rapid growth after passaging and reliable dopaminergic differentiation.Zeng X2004
15802089Combining research approaches to advance our understanding of drug addiction.van den Bree MB2005 Apr
15806583Association of the serotonin transporter promoter polymorphism with smoking behavior among adolescents.Gerra G2005 May 5
15814102Effect of acute and chronic psychostimulant drugs on redox status, AP-1 activation and pro-enkephalin mRNA in the human astrocyte-like U373 MG cells.Malaplate-Armand C2005 Apr
15816859Alcohol-responsive genes in the frontal cortex and nucleus accumbens of human alcoholics.Flatscher-Bader T2005 Apr
15829634cAMP-mediated mechanisms for pain sensitization during opioid withdrawal.Bie B2005 Apr 13
15832375Suicidal genetically engineered microorganisms for bioremediation: need and perspectives.Paul D2005 May
15834221Role of the serotonin transporter gene and family function in adolescent alcohol consumption.Nilsson KW2005 Apr
15837133Mouse brain localization of the protein kinase C-enhanced phosphatase 1 inhibitor KEPI (kinase C-enhanced PP1 inhibitor).Gong JP2005
15837145Methylphenidate (Ritalin) induces Homer 1a and zif 268 expression in specific corticostriatal circuits.Yano M2005
15841309Tissue plasminogen activator in central nervous system physiology and pathology.Melchor JP2005 Apr
15849013DNA microarrays and expression profiling in drug abuse research.Gebicke-Haerter PJ2005 Mar
15849017Expression profiling methods used in drug abuse research.Gebicke-Haerter P2005 Mar
15849018Expression profiling and QTL analysis: a powerful complementary strategy in drug abuse research.Spence J2005 Mar
15849019Using in vitro models for expression profiling studies on ethanol and drugs of abuse.Thibault C2005 Mar
15849021The search for candidate genes of alcoholism: evidence from expression profiling studies.Sommer W2005 Mar
15849024Microarray studies of psychostimulant-induced changes in gene expression.Yuferov V2005 Mar
15849025Gene expression profiling in the brains of human cocaine abusers.Bannon M2005 Mar
15852055Distinct proteomic profiles of amphetamine self-administration transitional states.Freeman WM2005
15856753[Genetically modified animals as models for psychiatric diseases]Sora I2005
15857384In vivo up-regulation of brain-derived neurotrophic factor in specific brain areas by chronic exposure to Delta-tetrahydrocannabinol.Butovsky E2005 May
15860252Evaluation of steroid receptor function by gene targeting in mice.Wintermantel TM2005 Feb
15870836Cluster B personality disorders are associated with allelic variation of monoamine oxidase A activity.Jacob CP2005 Sep
15879001Cocaine up-regulates Fra-2 and sigma-1 receptor gene and protein expression in brain regions involved in addiction and reward.Liu Y2005 Aug
15885214Electroacupuncture attenuates morphine withdrawal signs and c-Fos expression in the central nucleus of the amygdala in freely moving rats.Liu S2005 May 24
15886412Pharmacokinetics and metabolism of nicotine.Tutka P2005 Mar-Apr
15901780Regulation of alpha-synuclein expression in limbic and motor brain regions of morphine-treated mice.Ziolkowska B2005 May 18
15901784Endogenous kappa-opioid receptor systems regulate mesoaccumbal dopamine dynamics and vulnerability to cocaine.Chefer VI2005 May 18
15904717Expression of c-Fos in the rat central amygdala accompanies the acquisition but not expression of conditioned place aversion induced by withdrawal from acute morphine dependence.Jin C2005 Jun 3
15925706How individual sensitivity to opiates can be predicted by gene analyses.Ikeda K2005 Jun
15931675Adrenalectomy decreases corticotropin-releasing hormone gene expression and increases noradrenaline and dopamine extracellular levels in the rat lateral bed nucleus of the stria terminalis.Santibanez M2005 Jul 1
15944127The Ror receptor tyrosine kinase CAM-1 is required for ACR-16-mediated synaptic transmission at the C. elegans neuromuscular junction.Francis MM2005 May 19
15945062Picomolar concentrations of hibernation induction delta opioid peptide [D-Ala2,D-Leu5]enkephalin increase the nerve growth factor in NG-108 cells.Tsai SY2005 Sep 1
15950760Conditioned place preference associates with the mRNA expression of diazepam binding inhibitor in brain regions of the addicted rat during withdrawal.Liu X2005 Jun 13
15955630Genotype combinations for monoamine oxidase-B intron 13 polymorphism and dopamine D2 receptor TaqIB polymorphism are associated with ever-smoking status among men.Costa-Mallen P2005 Sep 9
15963538The dopamine D3 receptor and drug dependence: effects on reward or beyond?Le Foll B2005 Sep
15967985Regulation of dopaminergic transmission and cocaine reward by the Clock gene.McClung CA2005 Jun 28
15977398[The effect of ribozyme specially cleaving per1 mRNA on c-fos mRNA and its expression in hippocampus of morphine addicted mice]Liu YH2005 Apr
15978018The reinforcing effects of chronic D-amphetamine and morphine are impaired in a line of memory-deficient mice overexpressing calcineurin.Biala G2005 Jun
15994025Effect of fluoxetine and cocaine on the expression of clock genes in the mouse hippocampus and striatum.Uz T2005
15995696The genetics of addictions: uncovering the genes.Goldman D2005 Jul
16001069Nicotine reinforcement and cognition restored by targeted expression of nicotinic receptors.Maskos U2005 Jul 7
16001072Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma.Garraway LA2005 Jul 7
16011574Behavioral and neurochemical phenotyping of Homer1 mutant mice: possible relevance to schizophrenia.Szumlinski KK2005 Jul
16011579Genetic variation in heroin-induced changes in behaviour: effects of B6 strain dose on conditioned reward and locomotor sensitization in 129-B6 hybrid mice.Szumlinski KK2005 Jul
16018803Characterization of 17alpha-hydroxysteroid dehydrogenase activity (17alpha-HSD) and its involvement in the biosynthesis of epitestosterone.Bellemare V2005
16033423The POZ/BTB protein NAC1 interacts with two different histone deacetylases in neuronal-like cultures.Korutla L2005 Aug
16037950Increased AMPA GluR1 receptor subunit labeling on the plasma membrane of dendrites in the basolateral amygdala of rats self-administering morphine.Glass MJ2005 Oct
16039786Amygdalar vasopressin mRNA increases in acute cocaine withdrawal: evidence for opioid receptor modulation.Zhou Y2005
16046395Allelic expression imbalance of human mu opioid receptor (OPRM1) caused by variant A118G.Zhang Y2005 Sep 23
16046552Molecular consequences of silencing mutant K-ras in pancreatic cancer cells: justification for K-ras-directed therapy.Fleming JB2005 Jul
16049839International Narcotics Research--31st Conference.Fowler C2000 Oct
16054976Mechanisms of alcohol-associated cancers: introduction and summary of the symposium.Purohit V2005 Apr
16076954Gene expression evidence for remodeling of lateral hypothalamic circuitry in cocaine addiction.Ahmed SH2005 Aug 9
16084657Ultra-low-dose naloxone suppresses opioid tolerance, dependence and associated changes in mu opioid receptor-G protein coupling and Gbetagamma signaling.Wang HY2005
16084664Differential expression of arc mRNA and other plasticity-related genes induced by nicotine in adolescent rat forebrain.Schochet TL2005
16091475Pooled association genome scanning: validation and use to identify addiction vulnerability loci in two samples.Liu QR2005 Aug 16
16094367The hangover gene defines a stress pathway required for ethanol tolerance development.Scholz H2005 Aug 11
16099392Lipid signaling: sleep, synaptic plasticity, and neuroprotection.Chen C2005 Sep
16104378Gene expression differences in mice divergently selected for methamphetamine sensitivity.Palmer AA2005 May
16109588Polymorphism in the serotonin transporter gene and response to treatment in African American cocaine and alcohol-abusing individuals.Mannelli P2005 Sep
16109951The toxin-antitoxin system of the streptococcal plasmid pSM19035.Zielenkiewicz U2005 Sep
16115217Extracellular signal-regulated kinases (ERKs) modulate cocaine-induced gene expression in the mouse amygdala.Radwanska K2005 Aug
16123759NrCAM in addiction vulnerability: positional cloning, drug-regulation, haplotype-specific expression, and altered drug reward in knockout mice.Ishiguro H2006 Mar
16126608Genetic determinants of addiction to opioids and cocaine.Saxon AJ2005 Jul-Aug
16129461NIH symposium series: ingestive mechanisms in obesity, substance abuse and mental disorders.Simansky KJ2005 Sep 15
16139312Lewis and Fischer 344 strain differences in alpha2-adrenoceptors and tyrosine hydroxylase expression.Herradon G2006 Jan 18
16139315Neural systems recruited by drug- and food-related cues: studies of gene activation in corticolimbic regions.Kelley AE2005 Sep 15
16140056The role of cAMP response element-binding proteins in mediating stress-induced vulnerability to drug abuse.Kreibich AS2005
16141602Interindividual variability in nicotine metabolism: C-oxidation and glucuronidation.Nakajima M2005 Aug
16142050[Hepatitis C, interferon a and depression: main physiopathologic hypothesis]Vignau J2005 May-Jun
16146347Cocaine- and amphetamine-regulated transcript peptides play a role in drug abuse and are potential therapeutic targets.Kuhar MJ2005
16152573Significant association of BDNF haplotypes in European-American male smokers but not in European-American female or African-American smokers.Beuten J2005 Nov 5
16156052Alcohol consumption and the body's biological clock.Spanagel R2005 Aug
16157234Co-occurring DSM-IV drug abuse in DSM-IV drug dependence: results from the National Epidemiologic Survey on Alcohol and Related Conditions.Hasin DS2005 Oct 1
16166522Stability of EcoRI restriction-modification enzymes in vivo differentiates the EcoRI restriction-modification system from other postsegregational cell killing systems.Ichige A2005 Oct
16172612Differential protein expression in the prefrontal white matter of human alcoholics: a proteomics study.Alexander-Kaufman K2006 Jan
16176386Genetic basis for the psychostimulant effects of nicotine: a quantitative trait locus analysis in AcB/BcA recombinant congenic mice.Gill KJ2005 Oct
16179556Cocaine induces a differential dose-dependent alteration in the expression profile of immediate early genes, transcription factors, and caspases in PC12 cells: a possible mechanism of neurotoxic damage in cocaine addiction.Imam SZ2005 Aug
16181101Cell culture models of oxidative stress and injury in the central nervous system.Aksenova MV2005 Jan
16184603Confirmation of the association between a polymorphism in the promoter region of the prodynorphin gene and cocaine dependence.Dahl JP2005 Nov 5
16191666Functional polymorphism of the NQO2 gene is associated with methamphetamine psychosis.Ohgake S2005 Jun
16204638Cocaine and sigma-1 receptors modulate HIV infection, chemokine receptors, and the HPA axis in the huPBL-SCID model.Roth MD2005 Dec
16205370Expression of MBP, PLP, MAG, CNP, and GFAP in the Human Alcoholic Brain.Lewohl JM2005 Sep
16206910Use of herpes virus amplicon vectors to study brain disorders.Neve RL2005 Sep
16207873Behavioral sensitization to cocaine is associated with increased AMPA receptor surface expression in the nucleus accumbens.Boudreau AC2005 Oct 5
16219028Cocaine-induced CREB phosphorylation in nucleus accumbens of cocaine-sensitized rats is enabled by enhanced activation of extracellular signal-related kinase, but not protein kinase A.Mattson BJ2005 Dec
16223057COMBINE genetics study: the pharmacogenetics of alcoholism treatment response: genes and mechanisms.Goldman D2005 Jul
16243302Visualizing viral transduction of a cocaine-hydrolyzing, human butyrylcholinesterase in rats.Gao Y2005 Dec 15
16253227Individual differences in drug dependence in rats: the role of genetic factors and life events.Ellenbroek BA2005 Dec 5
16257473Comparison of basal and D-1 dopamine receptor agonist-stimulated neuropeptide gene expression in caudate-putamen and nucleus accumbens of ad libitum fed and food-restricted rats.Haberny SL2005 Nov 30
16263220Regulation of cocaine-induced activator protein 1 transcription factors by the extracellular signal-regulated kinase pathway.Radwanska K2006
16266816Application of a KDPG-aldolase gene-dependent addiction system for enhanced production of cyanophycin in Ralstonia eutropha strain H16.Voss I2006 Jan
16269905Norepinephrine transporter: a candidate gene for initial ethanol sensitivity in inbred long-sleep and short-sleep mice.Haughey HM2005 Oct
16280577Epigenetic mechanisms and gene networks in the nervous system.Colvis CM2005 Nov 9
16282533HIV-1 TAT represses transcription of the bone morphogenic protein receptor-2 in U937 monocytic cells.Caldwell RL2006 Jan
16286246Reduction in the requirement of oncogenic Ras signaling to activation of PI3K/AKT pathway during tumor maintenance.Lim KH2005 Nov
16288736Alcohol dependence and gene x environment interaction in emotion regulation: Is serotonin the link?Lesch KP2005 Dec 5
16289352Chronic and acute effects of 3,4-methylenedioxy-N-methylamphetamine ('Ecstasy') administration on the dynorphinergic system in the rat brain.Di Benedetto M2006
16299387Genetic addiction: selfish gene's strategy for symbiosis in the genome.Mochizuki A2006 Feb
16299503The prolactin-releasing peptide antagonizes the opioid system through its receptor GPR10.Laurent P2005 Dec
16310935Role of glucocorticoids in dopamine-related neuropsychiatric disorders.Van Craenenbroeck K2005 Dec 21
16314761A functional prodynorphin promoter polymorphism and opioid dependence.Ray R2005 Dec
16314880(AAT)n repeat in the cannabinoid receptor gene (CNR1): association with cocaine addiction in an African-Caribbean population.Ballon N2006 Mar-Apr
16326019Gene expression regulation following behavioral sensitization to cocaine in transgenic mice lacking the glucocorticoid receptor in the brain.Izawa R2006 Feb
16338084Methamphetamine and human immunodeficiency virus protein Tat synergize to destroy dopaminergic terminals in the rat striatum.Theodore S2006 Feb
16339038Parsing molecular and behavioral effects of cocaine in mitogen- and stress-activated protein kinase-1-deficient mice.Brami-Cherrier K2005 Dec 7
16339307The corticotropin-releasing factor receptor-1 pathway mediates the negative affective states of opiate withdrawal.Contarino A2005 Dec 20
16344716Pharmacogenetics of opioid receptors and addiction.Mayer P2006 Jan
16344719Association analysis of polymorphisms in serotonin 1B receptor (HTR1B) gene with heroin addiction: a comparison of molecular and statistically estimated haplotypes.Proudnikov D2006 Jan
16356622Fos, nociception and the dorsal horn.Coggeshall RE2005 Dec
16358338Allele C-specific methylation of the 5-HT2A receptor gene: evidence for correlation with its expression and expression of DNA methylase DNMT1.Polesskaya OO2006 Feb 15
16359811Antisense-induced reduction in nucleus accumbens cyclic AMP response element binding protein attenuates cocaine reinforcement.Choi KH2006
16367982Addiction and its brain science.Spanagel R2005 Dec
16368555Gene chromosomal organization and expression in cultured human neurons exposed to cocaine and HIV-1 proteins gp120 and tat: drug abuse and NeuroAIDS.Shapshak P2006
16369835Cocaine self-administration under fixed and progressive ratio schedules of reinforcement: comparison of C57BL/6J, 129X1/SvJ, and 129S6/SvEvTac inbred mice.Thomsen M2006 Jan
16371314Methamphetamine-induced neuronal apoptosis involves the activation of multiple death pathways. Review.Cadet JL2005 Nov
16376315Rodent BDNF genes, novel promoters, novel splice variants, and regulation by cocaine.Liu QR2006 Jan 5
16380209Trifluoperazine, an orally available clinically used drug, disrupts opioid antinociceptive tolerance.Tang L2006 Apr 10-17
16380431CREB-binding protein controls response to cocaine by acetylating histones at the fosB promoter in the mouse striatum.Levine AA2005 Dec 27
16385640Role of adenosine in the control of homosynaptic plasticity in striatal excitatory synapses.Ferre S2005 Dec
16390452MazG -- a regulator of programmed cell death in Escherichia coli.Gross M2006 Jan
16395306Motor-skill learning-associated gene regulation in the striatum: effects of cocaine.Willuhn I2006 Dec
16402083Linkage disequilibrium and association with methamphetamine dependence/psychosis of mu-opioid receptor gene polymorphisms.Ide S2006 May-Jun
16407894Knockout of ERK1 enhances cocaine-evoked immediate early gene expression and behavioral plasticity.Ferguson SM2006 Dec
16408195GABAergic lineage differentiation of AF5 neural progenitor cells in vitro.Sanchez JF2006 Apr
16412997Contingency does not contribute to the effects of cocaine self-administration on prodynorphin and proenkephalin gene expression in the rat forebrain.Ziolkowska B2006 Jan 19
16413467BuCy RAFs drive cells into MEK addiction.Rapp UR2006 Jan
16415864An essential role for DeltaFosB in the nucleus accumbens in morphine action.Zachariou V2006 Feb
16415919Relevance of frequent mu-opioid receptor polymorphisms for opioid activity in healthy volunteers.Lotsch J2006 May-Jun
16430700The chromosomal relBE2 toxin-antitoxin locus of Streptococcus pneumoniae: characterization and use of a bioluminescence resonance energy transfer assay to detect toxin-antitoxin interaction.Nieto C2006 Feb
16447156Intermittent administration of morphine alters protein expression in rat nucleus accumbens.Li KW2006 Mar
16451628Description of the data from the Collaborative Study on the Genetics of Alcoholism (COGA) and single-nucleotide polymorphism genotyping for Genetic Analysis Workshop 14.Edenberg HJ2005 Dec 30
16452681Cocaine increases actin cycling: effects in the reinstatement model of drug seeking.Toda S2006 Feb 1
16452987Stimulation of adenosine receptors selectively activates gene expression in striatal enkephalinergic neurons.Karcz-Kubicha M2006 Oct
16453311Chronic morphine treatment alters expression of N-methyl-D-aspartate receptor subunits in the extended amygdala.Bajo M2006 Mar
16461907Amplification of MET may identify a subset of cancers with extreme sensitivity to the selective tyrosine kinase inhibitor PHA-665752.Smolen GA2006 Feb 14
16472786Cannabinoid CB2 receptors: immunohistochemical localization in rat brain.Gong JP2006 Feb 3
16473275TORgeting oncogene addiction for cancer therapy.Choo AY2006 Feb
16475094Ontogeny of additive and maternal genetic effects: lessons from domestic mammals.Wilson AJ2006 Jan
16490314Characterization of the neuronal dopamine transporter DAT in human blood platelets.Frankhauser P2006 May 22
16491070Epigenetic gene silencing in cancer - a mechanism for early oncogenic pathway addiction?Baylin SB2006 Feb
16506415Methods to study the behavioral effects and expression of CB2 cannabinoid receptor and its gene transcripts in the chronic mild stress model of depression.Onaivi ES2006
16510141Involvement of cytokines in human immunodeficiency virus-1 protein Tat and methamphetamine interactions in the striatum.Theodore S2006 Jun
16513365Chronic exposure to Delta9-tetrahydrocannabinol downregulates oxytocin and oxytocin-associated neurophysin in specific brain areas.Butovsky E2006 Apr
16526025MAOA-uVNTR polymorphism in a Brazilian sample: further support for the association with impulsive behaviors and alcohol dependence.Contini V2006 Apr 5
16537431A dopamine transporter gene functional variant associated with cocaine abuse in a Brazilian sample.Guindalini C2006 Mar 21
16537460Adenylyl cyclase type 5 (AC5) is an essential mediator of morphine action.Kim KS2006 Mar 7
16539670Ethanol enhancement of cocaine- and amphetamine-regulated transcript mRNA and peptide expression in the nucleus accumbens.Salinas A2006 Apr
16539683Acute amphetamine down-regulates RGS4 mRNA and protein expression in rat forebrain: distinct roles of D1 and D2 dopamine receptors.Schwendt M2006 Mar
16539891An overview of the genetics of substance use disorders.Lachman HM2006 Apr
16573576Endogenous kappa opioid receptor systems modulate the responsiveness of mesoaccumbal dopamine neurons to ethanol.Zapata A2006 Apr
16585131Fluoroquinolone resistance and plasmid addiction systems: self-imposed selection pressure?Ellington MJ2006 Jun
16597437Increases in preproenkephalin mRNA levels in the Syrian hamster: the influence of glucocorticoids is dependent on age and tissue.Franklin SO2006 May 1
16618939Toward understanding the genetics of alcohol drinking through transcriptome meta-analysis.Mulligan MK2006 Apr 18
16631145cis-Regulatory sequences of the genes involved in apoptosis, cell growth, and proliferation may provide a target for some of the effects of acute ethanol exposure.Uddin RK2006 May 9
16631172The role of NR2B containing NMDA receptor in place preference conditioned with morphine and natural reinforcers in rats.Ma YY2006 Aug
16642357Dopamine D4 receptor polymorphism modulates cue-elicited heroin craving in Chinese.Shao C2006 Apr 27
16643512Defining the dopamine transporter proteome by convergent biochemical and in silico analyses.Maiya R2007 Feb
16644101Gene expression patterns for GDNF and its receptors in the human putamen affected by Parkinson's disease: a real-time PCR study.Backman CM2006 Jun 27
16644901Neuroproteomics of the synapse and drug addiction.Abul-Husn NS2006 Aug
16645894Epinephrine biosynthesis: hormonal and neural control during stress.Wong DL2006 Jul-Aug
16651427Validation of met as a therapeutic target in alveolar and embryonal rhabdomyosarcoma.Taulli R2006 May 1
16675138Reduced expression and capacity of the striatal high-affinity choline transporter in hyperdopaminergic mice.Parikh V2006 Aug 11
16684513CB1 knockout mice display significant changes in striatal opioid peptide and D4 dopamine receptor gene expression.Gerald TM2006 Jun 6
16684876Adenosine A2a blockade prevents synergy between mu-opiate and cannabinoid CB1 receptors and eliminates heroin-seeking behavior in addicted rats.Yao L2006 May 16
16691130Influence of the serotonin transporter gene on comorbid disorders among alcohol-dependent individuals.Marques FZ2006 Jun
16697078CART peptide diurnal variations in blood and brain.Vicentic A2006 Aug
16697650Increased vulnerability of ApoE4 neurons to HIV proteins and opiates: protection by diosgenin and L-deprenyl.Turchan-Cholewo J2006 Jul
16698049Adolescent and adult responsiveness to the incentive value of cocaine reward in mice: role of neuronal nitric oxide synthase (nNOS) gene.Balda MA2006 Aug
16703401Dopamine D4 receptor polymorphism modulates cue-elicited heroin craving in Chinese.Shao C2006 Jun
16704932Homer proteins: implications for neuropsychiatric disorders.Szumlinski KK2006 Jun
16708286Viral transduction of cocaine hydrolase in brain reward centers.Gao Y2006 Jul-Aug
16710311Heteromeric nicotinic acetylcholine-dopamine autoreceptor complexes modulate striatal dopamine release.Quarta D2007 Jan
16710320Distinctive profiles of gene expression in the human nucleus accumbens associated with cocaine and heroin abuse.Albertson DN2006 Oct
16721846Molecular analysis and phylogenetic characterization of HIV in Iran.Sarrami-Forooshani R2006 Jul
16722244ADHD and the dopamine transporter: are there reasons to pay attention?Mazei-Robinson MS2006
16729985Protein expression profile in the striatum of acute methamphetamine-treated rats.Iwazaki T2006 Jun 30
16740610Gene expression profiles of brain dopamine neurons and relevance to neuropsychiatric disease.Greene JG2006 Sep 1
16741673Three types of tyrosine hydroxylase-positive CNS neurons distinguished by dopa decarboxylase and VMAT2 co-expression.Weihe E2006 Jul-Aug
16741914Association analysis of delta-opioid receptor gene polymorphisms in methamphetamine dependence/psychosis.Kobayashi H2006 Jul 5
16753266Preliminary study of the effects of morphine treatment on opioid receptor gene expression in brain structures of the female rat.Teodorov E2006 Sep 1
16771829C/EBPbeta couples dopamine signalling to substance P precursor gene expression in striatal neurones.Kovacs KA2006 Sep
16776832Forebrain overexpression of CaMKII abolishes cingulate long term depression and reduces mechanical allodynia and thermal hyperalgesia.Wei F2006
16777354Biological research on drug abuse and addiction in Hispanics: current status and future directions.Trujillo KA2006 Sep
16783631Expression genetics and the phenotype revolution.Williams RW2006 Jun
16787186Amplicon vectors as outstanding tools to study and modify cognitive functions.Jerusalinsky D2006 Jun
16787418Enhanced cortical and accumbal molecular reactivity associated with conditioned heroin, but not sucrose-seeking behaviour.Koya E2006 Aug
16799083Understanding our drugs and our diseases.Guo Y2006 Jul
16800848Activation of D1 dopamine receptors increases surface expression of AMPA receptors and facilitates their synaptic incorporation in cultured hippocampal neurons.Gao C2006 Sep
16815213Molecular genetics of addiction vulnerability.Uhl GR2006 Jul
16820221Nucleoside transporters: from scavengers to novel therapeutic targets.King AE2006 Aug
16822586Cocaine and amphetamine regulated transcript (CART) and the stress response.Koylu EO2006 Aug
16823388Beta1 adrenergic receptors in the bed nucleus of stria terminalis mediate differential responses to opiate withdrawal.Cecchi M2007 Mar
16823800An association study of the brain-derived neurotrophic factor Val66Met polymorphism and amphetamine response.Flanagin BA2006 Sep 5
16824691Increased central brain-derived neurotrophic factor activity could be a risk factor for substance abuse: Implications for treatment.Tsai SJ2007
16831471CCR2 mediates increases in glial activation caused by exposure to HIV-1 Tat and opiates.El-Hage N2006 Sep
16840648The CART (cocaine- and amphetamine-regulated transcript) system in appetite and drug addiction.Vicentic A2007 Feb
16845230Helicobacter pylori inhibits expression of heat shock protein 70 (HSP70) in human epithelial cell line. Importance of Cag A protein.Targosz A2006 Jun
16845490ACTH receptor: ectopic expression, activity and signaling.Forti FL2006 Dec
16855532Differential regulation of immediate-early gene expression in the prefrontal cortex of rats with a high vs low behavioral response to methamphetamine.Shilling PD2006 Nov
16857816"Oncogenic shock": explaining oncogene addiction through differential signal attenuation.Sharma SV2006 Jul 15
16862190Lineage dependency and lineage-survival oncogenes in human cancer.Garraway LA2006 Aug
16865686Characterization of a mouse strain expressing Cre recombinase from the 3' untranslated region of the dopamine transporter locus.Backman CM2006 Aug
16869735"Lineage addiction" in human cancer: lessons from integrated genomics.Garraway LA2005
16869776Is oncogene addiction angiogenesis-dependent?Folkman J2005
16869779Molecular targeted therapy of lung cancer: EGFR mutations and response to EGFR inhibitors.Haber DA2005
16876260Intracellular 5-HT 2C-receptor dephosphorylation: a new target for treating drug addiction.Muller CP2006 Sep
16889689GEDA: new knowledge base of gene expression in drug addiction.Suh YJ2006 Jul 31
16892316Using ColE1-derived RNA I for suppression of a bacterially encoded gene: implication for a novel plasmid addiction system.Pfaffenzeller I2006 Jun
16894390Mechanisms of disease: Oncogene addiction--a rationale for molecular targeting in cancer therapy.Weinstein IB2006 Aug
16894595Linkage disequilibrium, haplotype and association studies of a chromosome 4 GABA receptor gene cluster: candidate gene variants for addictions.Drgon T2006 Dec 5
16901644Imaging gene-substance interactions: the effect of the DRD2 TaqIA polymorphism and the dopamine agonist bromocriptine on the brain activation during the anticipation of reward.Kirsch P2006 Sep 25
16906354Nicotinic receptor agonists as neuroprotective/neurotrophic drugs. Progress in molecular mechanisms.Mudo G2007 Jan
16930369A genetic association study of dopamine metabolism-related genes and chronic headache with drug abuse.Cevoli S2006 Sep
16930414Cocaine-induced locomotor activity and Fos expression in nucleus accumbens are sensitized for 6 months after repeated cocaine administration outside the home cage.Hope BT2006 Aug
16950574Association of THR105Ile, a functional polymorphism of histamine N-methyltransferase (HNMT), with alcoholism in German Caucasians.Reuter M2007 Feb 23
16952495Comprehensive evaluation of variability in nicotine metabolism and CYP2A6 polymorphic alleles in four ethnic populations.Nakajima M2006 Sep
16963576Bile-induced curing of the virulence plasmid in Salmonella enterica serovar Typhimurium.Garcia-Quintanilla M2006 Nov
16966188Serotonin transporter genotype and acute subjective response to amphetamine.Lott DC2006 Sep-Oct
16972078The fatty acid amide hydrolase 385 A/A (P129T) variant: haplotype analysis of an ancient missense mutation and validation of risk for drug addiction.Flanagan JM2006 Nov
16972224Perceived parenting behavior in the childhood of cocaine users: relationship with genotype and personality traits.Gerra G2007 Jan 5
16982424Leptin receptor signaling in midbrain dopamine neurons regulates feeding.Hommel JD2006 Sep 21
16988036Altered attention and prefrontal cortex gene expression in rats after binge-like exposure to cocaine during adolescence.Black YD2006 Sep 20
16988049Identification of sequence motifs that target neuronal nicotinic receptors to dendrites and axons.Xu J2006 Sep 20
17008016Divergent anatomical pattern of D1 and D3 binding and dopamine- and cyclic AMP-regulated phosphoprotein of 32 kDa mRNA expression in the Roman rat strains: Implications for drug addiction.Guitart-Masip M2006 Nov 3
17010096Dissociation of food and opiate preference by a genetic mutation in zebrafish.Lau B2006 Oct
17014870Sensitization to the conditioned rewarding effects of morphine modulates gene expression in rat hippocampus.Marie-Claire C2007 Feb
17017966Central serotonin2C receptor: from physiology to pathology.Di Giovanni G2006
17018022Regulation of mitogen-activated protein kinases by glutamate receptors.Wang JQ2007 Jan
17023388Autoregulation of glial cell line-derived neurotrophic factor expression: implications for the long-lasting actions of the anti-addiction drug, Ibogaine.He DY2006 Nov
17027697Assessment of genome and proteome profiles in cocaine abuse.Hemby SE2006
17027765Relative expression of D3 dopamine receptor and alternative splice variant D3nf mRNA in high and low responders to novelty.Pritchard LM2006 Oct 16
17030115Effects of constitutive deletion of opioid receptors on the basal densities of Fas and Fas-associated protein with death domain (FADD) in the mouse brain: a delta-opioid tone inhibits FADD.Garcia-Fuster MJ2007 Apr
17038198TasA-tasB, a new putative toxin-antitoxin (TA) system from Bacillus thuringiensis pGI1 plasmid is a widely distributed composite mazE-doc TA system.Fico S2006
17049170A threshold neurotoxic amphetamine exposure inhibits parietal cortex expression of synaptic plasticity-related genes.Bowyer JF2007 Jan 5
17050719Blockade of adenosine A2A receptors prevents protein phosphorylation in the striatum induced by cortical stimulation.Quiroz C2006 Oct 18
17059838Cocaine increases 5-HT1B mRNA in rat nucleus accumbens shell neurons.Hoplight BJ2007 Feb
17063402Genetics of dopamine and its contribution to cocaine addiction.Haile CN2007 Jan
17064752SIV Vpr evolution is inversely related to disease progression in a morphine-dependent rhesus macaque model of AIDS.Noel RJ Jr2007 Mar 15
17067345Glutamate decarboxylase genes and alcoholism in Han Taiwanese men.Loh el-W2006 Nov
17081571Chronic food restriction: enhancing effects on drug reward and striatal cell signaling.Carr KD2007 Aug 15
17097564A common signaling cascade may underlie "addiction" to the Src, BCR-ABL, and EGF receptor oncogenes.Sharma SV2006 Nov
17098214Distinct patterns of neural activation associated with ethanol seeking: effects of naltrexone.Dayas CV2007 Apr 15
17099884Addiction molecular genetics: 639,401 SNP whole genome association identifies many "cell adhesion" genes.Liu QR2006 Dec 5
17101067The molecular pathogenesis of gastrointestinal stromal tumors.Tarn C2006 Nov
17105900Serial analysis of gene expression in the rat striatum following methamphetamine administration.Cai NS2006 Aug
17105950Discovery of the presence and functional expression of cannabinoid CB2 receptors in brain.Onaivi ES2006 Aug
17106427Human clock, PER1 and PER2 polymorphisms: lack of association with cocaine dependence susceptibility and cocaine-induced paranoia.Malison RT2006 Dec
17106428Association analysis of the NrCAM gene in autism and in subsets of families with severe obsessive-compulsive or self-stimulatory behaviors.Sakurai T2006 Dec
17107706How gene-stress-behavior interactions can promote adolescent alcohol use: the roles of predrinking allostatic load and childhood behavior disorders.Zimmermann US2007 Feb
17116233Emerging concepts: novel integration of in vivo approaches to localize the function of nicotinic receptors.Maskos U2007 Feb
17117962Ethanol-induced regulation of GABA-A subunit mRNAs in prefrontal fields of cynomolgus monkeys.Hemby SE2006 Dec
17123717Yohimbine prevents morphine-induced changes of glial fibrillary acidic protein in brainstem and alpha2-adrenoceptor gene expression in hippocampus.Alonso E2007 Jan 29
17139840The molecular mechanisms of morphine addiction.McClung CA2006
17141149Oncogene addiction: role of signal attenuation.Hubner A2006 Dec
17147699Drug reward and intake in lines of mice selectively bred for divergent exploration of a hole board apparatus.Kliethermes CL2007 Oct
17149751Mouse and rat BDNF gene structure and expression revisited.Aid T2007 Feb 15
17157823Effect of mu-opioid receptor gene polymorphisms on heroin-induced subjective responses in a Chinese population.Zhang D2007 Jun 1
17167830The genetics of nicotine dependence: relationship to pancreatic cancer.MacLeod SL2006 Dec 14
17182779c-Fos facilitates the acquisition and extinction of cocaine-induced persistent changes.Zhang J2006 Dec 20
17182791Hypocretin/orexin overexpression induces an insomnia-like phenotype in zebrafish.Prober DA2006 Dec 20
17186223Association of the met66 allele of brain-derived neurotrophic factor (BDNF) with smoking.Lang UE2007 Mar
17187009The COMT Val158Met polymorphism is associated with novelty seeking in Czech methamphetamine abusers: preliminary results.Hosak L2006 Dec
17200667Nucleotide sequence variation within the human tyrosine kinase B neurotrophin receptor gene: association with antisocial alcohol dependence.Xu K2007 Jan 2
17203488Alterations in prodynorphin, proenkephalin, and GAD67 mRNA levels in the aged human putamen: correlation with Parkinson's disease.Backman CM2007 Mar
17205118Transcriptional changes common to human cocaine, cannabis and phencyclidine abuse.Lehrmann E2006
17224913Overview of the pharmacogenomics of cigarette smoking.Ho MK2007 Apr
17226102Intravenous drug self-administration in mice: practical considerations.Thomsen M2007 Jan

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